Thyroid Stimulating Hormone Suppression in the Long-term Follow-up of Differentiated Thyroid Cancer

被引：21

作者：

Freudenthal, B. ^{[1
]}

Williams, G. R. ^{[1
]}

机构：

[1] Imperial Coll London, Mol Endocrinol Lab, Hammersmith Campus,10N5 Commonwealth Bldg, London W12 0NN, England

来源：

CLINICAL ONCOLOGY | 2017年 / 29卷 / 05期

关键词：

Differentiated thyroid cancer; subclinical thyrotoxicosis; TSH suppression; SERUM THYROTROPIN CONCENTRATIONS; ATRIAL-FIBRILLATION; TSH SUPPRESSION; SUBCLINICAL HYPERTHYROIDISM; CARDIOVASCULAR MORTALITY; THERAPY; CARCINOMA; RISK; LEVOTHYROXINE; MANAGEMENT;

D O I：

10.1016/j.clon.2016.12.011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Differentiated thyroid cancer is the most common form of thyroid cancer and its prognosis is favourable in most cases. Suppression of thyroid stimulating hormone (TSH) by supra-physiological thyroid hormone replacement has been the mainstay of long-term management for over 60 years. However, evidence for a beneficial outcome of TSH suppression is conflicting and intervention must be balanced against adverse effects, particularly affecting the cardiovascular system and skeleton. Here we discuss the role of TSH suppression in the long-term management of differentiated thyroid cancer in the context of risk stratification for disease recurrence and the latest clinical guidelines. (C) 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

引用

页码：325 / 328

页数：4

共 34 条

[1] Both Exogenous Subclinical Hyperthyroidism and Short-Term Overt Hypothyroidism Affect Myocardial Strain in Patients with Differentiated Thyroid Carcinoma [J].

Abdulrahman, Randa M. ;

Delgado, Victoria ;

Hoftijzer, Hendrieke C. ;

Ng, Arnold C. T. ;

Ewe, See Hooi ;

Marsan, Nina Ajmone ;

Holman, Eduard R. ;

Hovens, Guido C. ;

Corssmit, Eleonora P. ;

Romijn, Johannes A. ;

Bax, Jeroen J. ;

Smit, Johannes W. A. .

THYROID, 2011, 21 (05) :471-476

[2]

Abonowara A, 2012, CLIN INVEST MED, V35, pE152

[3] Role of Thyroid Hormones in Skeletal Development and Bone Maintenance [J].

Bassett, J. H. Duncan ;

Williams, Graham R. .

ENDOCRINE REVIEWS, 2016, 37 (02) :135-187

[4] CARDIAC EFFECTS OF LONG-TERM THYROTROPIN-SUPPRESSIVE THERAPY WITH LEVOTHYROXINE [J].

BIONDI, B ;

FAZIO, S ;

CARELLA, C ;

AMATO, G ;

CITTADINI, A ;

LUPOLI, G ;

SACCA, L ;

BELLASTELLA, A ;

LOMBARDI, G .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1993, 77 (02) :334-338

[5] Reentrant atrioventricular nodal tachycardia induced by levothyroxine [J].

Biondi, B ;

Fazio, S ;

Coltorti, F ;

Palmieri, EA ;

Carella, C ;

Lombardi, G ;

Saccà, L .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (08) :2643-2645

[6] Benefits of Thyrotropin Suppression Versus the Risks of Adverse Effects in Differentiated Thyroid Cancer [J].

Biondi, Bernadette ;

Cooper, David S. .

THYROID, 2010, 20 (02) :135-146

[7] Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration [J].

Boelaert, K. ;

Horacek, J. ;

Holder, R. L. ;

Watkinson, J. C. ;

Sheppard, M. C. ;

Franklyn, J. A. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (11) :4295-4301

[8] Subclinical Hyperthyroidism and the Risk of Coronary Heart Disease and Mortality [J].

Collet, Tinh-Hai ;

Gussekloo, Jacobijn ;

Bauer, Douglas C. ;

den Elzen, Wendy P. J. ;

Cappola, Anne R. ;

Balmer, Philippe ;

Iervasi, Giorgio ;

Asvold, Bjorn O. ;

Sgarbi, Jose A. ;

Voelzke, Henry ;

Gencer, Baris ;

Maciel, Rui M. B. ;

Molinaro, Sabrina ;

Bremner, Alexandra ;

Luben, Robert N. ;

Maisonneuve, Patrick ;

Cornuz, Jacques ;

Newman, Anne B. ;

Khaw, Kay-Tee ;

Westendorp, Rudi G. J. ;

Franklyn, Jayne A. ;

Vittinghoff, Eric ;

Walsh, John P. ;

Rodondi, Nicolas .

ARCHIVES OF INTERNAL MEDICINE, 2012, 172 (10) :799-809

[9] Thyrotropin suppression and disease progression in patients with differentiated thyroid cancer: Results from the National Thyroid Cancer Treatment Cooperative Registry [J].

Cooper, DS ;

Specker, B ;

Ho, M ;

Sperling, M ;

Ladenson, PW ;

Ross, DS ;

Ain, KB ;

Bigos, ST ;

Brierley, JD ;

Haugen, BR ;

Klein, I ;

Robbins, J ;

Sherman, SI ;

Taylor, T ;

Maxon, HR .

THYROID, 1998, 8 (09) :737-744

[10] Impact of moderate vs stringent TSH suppression on survival in advanced differentiated thyroid carcinoma [J].

Diessl, Stefanie ;

Holzberger, Barbara ;

Maeder, Uwe ;

Grelle, Inge ;

Smit, Johannes W. A. ;

Buck, Andreas K. ;

Reiners, Christoph ;

Verburg, Frederik A. .

CLINICAL ENDOCRINOLOGY, 2012, 76 (04) :586-592

← 1 2 3 4 →