Formation of nano-patterned protein layers on poly (lactic acid) surface: Induced by dewetting process and self-assembly

被引：6
|
作者：
Liang, Zhi-Hong [1 ]
Zhou, Chang-Ren [2 ]
Zeng, Rong [2 ]
Zhang, Yi [2 ]
Yin, Ping-He [1 ]
机构：
[1] Jinan Univ, Expt & Technol Ctr, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Dept Mat Sci, Guangzhou 510632, Guangdong, Peoples R China
来源：
MATERIALS LETTERS | 2009年 / 63卷 / 11期
基金：
中国国家自然科学基金;
关键词：
Poly (lactic acid); Type I collagen; Atomic force microscopy; Dewetting; Surfaces; ADSORBED COLLAGEN; ORGANIZATION; ADSORPTION;
D O I：
10.1016/j.matlet.2009.01.059
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A simple method was developed to fabricate nano-patterned protein layers on poly (lactic acid) (PLA) Surface by dewetting method. it was found that nano-patterned protein layers were formed on PLA surface by slow drying in high humidity. The influence of wettability and viscoelastic properties of substrates were also investigated. As a result, typical spinodal dewetting patterns formed for BSA. However, network structures were obtained for collagen at acidic condition and well-oriented fibrils at neutral pH. It was attributed to dewetting on hydrophobic substrate as well as the plasticity and variety of collagen self-assemblies. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：927 / 929
页数：3
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