The Effect of Dihydroquercetin on Catalytic Activity of Iron (II) Ions in the Fenton Reaction

被引：16
作者：
Babenkova, I. V. [1 ]
Osipov, A. N. [1 ]
Teselkin, Yu. O. [1 ]
机构：
[1] NI Pirogov Russian Natl Res Med Univ, Dept Med Biophys, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2018年 / 165卷 / 03期
关键词：
dihydroquercetin; taxifolin; chelation of iron ions; Fenton reaction; chemiluminescence; ANTIOXIDANT ACTIVITY; FLAVONOIDS; PROOXIDANT; TAXIFOLIN;
D O I：
10.1007/s10517-018-4167-x
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Dihydroquercetin is a natural flavonoid with antioxidant properties that are determined by its ability to scavenge free radicals and chelate transition metal ions. Chemiluminescent studies showed that iron (II) ions in complex with dihydroquercetin are inactive and cannot catalyze decomposition of hydrogen peroxide (Fenton reaction).
引用
收藏
页码：347 / 350
页数：4
相关论文
共 15 条
  • [1] Antioxidant and prooxidant behavior of flavonoids: Structure-activity relationships
    Cao, GH
    Sofic, E
    Prior, RL
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1997, 22 (05) : 749 - 760
  • [2] Determination of antioxidant activity of phenolic antioxidants in a Fenton-type reaction system by chemiluminescence assay
    Cheng, ZY
    Yan, GT
    Li, YZ
    Chang, WB
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2003, 375 (05) : 376 - 380
  • [3] Exploration of pro-oxidant and antioxidant activities of the flavonoid myricetin
    Chobot, Vladimir
    Hadacek, Franz
    [J]. REDOX REPORT, 2011, 16 (06) : 242 - 247
  • [4] Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects
    Gammella, Elena
    Recalcati, Stefania
    Cairo, Gaetano
    [J]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2016, 2016
  • [5] Advances in metal-induced oxidative stress and human disease
    Jomova, Klaudia
    Valko, Marian
    [J]. TOXICOLOGY, 2011, 283 (2-3) : 65 - 87
  • [6] Klebanov G I, 1998, Membr Cell Biol, V12, P89
  • [7] Flavonoids as antioxidants
    Pietta, PG
    [J]. JOURNAL OF NATURAL PRODUCTS, 2000, 63 (07): : 1035 - 1042
  • [8] Plotnikov MB, 2005, DIQUERTIN BASED DRUG
  • [9] Antioxidant and iron-chelating properties of taxifolin and its condensation product with glyoxylic acid
    Shubina, Victoria S.
    Shatalin, Yuri V.
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2017, 54 (06): : 1467 - 1475
  • [10] Thiamine inhibits formation of dityrosine, a specific marker of oxidative injury, in reactions catalyzed by oxoferryl forms of hemoglobin
    Stepuro, A. I.
    Adamchuk, R. I.
    Oparin, A. Yu.
    Stepuro, I. I.
    [J]. BIOCHEMISTRY-MOSCOW, 2008, 73 (09) : 1031 - 1041
12