Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association

被引:167
作者
Topjian, Alexis A. [1 ]
de Caen, Allan [7 ,8 ]
Wainwright, Mark S. [13 ]
Abella, Benjamin S. [3 ]
Abend, Nicholas S. [4 ]
Atkins, Dianne L. [5 ]
Bembea, Melania M. [6 ]
Fink, Ericka L. [9 ]
Guerguerian, Anne-Marie [2 ]
Haskell, Sarah E. [5 ]
Kilgannon, J. Hope [11 ]
Lasa, Javier J. [12 ]
Hazinski, Mary Fran [10 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[2] Hosp Sick Children, 555 Univ Ave, Toronto, ON, Canada
[3] Univ Penn, Philadelphia, PA 19104 USA
[4] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[5] Univ Iowa, Iowa City, IA 52242 USA
[6] Johns Hopkins Univ, Baltimore, MD 21218 USA
[7] Univ Alberta, Edmonton, AB, Canada
[8] Stollery Childrens Hosp, Edmonton, AB, Canada
[9] UPMC, Childrens Hosp Pittsburgh, Pittsburgh, PA USA
[10] Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA
[11] Cooper Univ Hosp, Camden, NJ USA
[12] Texas Childrens Hosp, Baylor Coll Med, Houston, TX 77030 USA
[13] Northwestern Univ, Evanston, IL 60208 USA
关键词
AHA Scientific Statements; cardiopulmonary arrest; cardiopulmonary resuscitation; child; outcomes; post-cardiac arrest care; targeted temperature management; TARGETED TEMPERATURE MANAGEMENT; ADVANCED LIFE-SUPPORT; MILD THERAPEUTIC HYPOTHERMIA; EXTRACORPOREAL CARDIOPULMONARY-RESUSCITATION; CEREBRAL-BLOOD-FLOW; QUALITY-OF-LIFE; EARLY POSTRESUSCITATION HYPOTENSION; HOSPITAL VENTRICULAR-FIBRILLATION; ELECTROGRAPHIC STATUS EPILEPTICUS; RELATIVE ADRENAL INSUFFICIENCY;
D O I
10.1161/CIR.0000000000000697
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Successful resuscitation from cardiac arrest results in a post-cardiac arrest syndrome, which can evolve in the days to weeks after return of sustained circulation. The components of post-cardiac arrest syndrome are brain injury, myocardial dysfunction, systemic ischemia/reperfusion response, and persistent precipitating pathophysiology. Pediatric post-cardiac arrest care focuses on anticipating, identifying, and treating this complex physiology to improve survival and neurological outcomes. This scientific statement on post-cardiac arrest care is the result of a consensus process that included pediatric and adult emergency medicine, critical care, cardiac critical care, cardiology, neurology, and nursing specialists who analyzed the past 20 years of pediatric cardiac arrest, adult cardiac arrest, and pediatric critical illness peer-reviewed published literature. The statement summarizes the epidemiology, pathophysiology, management, and prognostication after return of sustained circulation after cardiac arrest, and it provides consensus on the current evidence supporting elements of pediatric post-cardiac arrest care.
引用
收藏
页码:E194 / E233
页数:40
相关论文
共 335 条
[31]   New concepts in reactive oxygen species and cardiovascular reperfusion physiology [J].
Becker, LB .
CARDIOVASCULAR RESEARCH, 2004, 61 (03) :461-470
[32]   Functional outcomes of school-age children with acquired brain injuries at discharge from inpatient rehabilitation [J].
Bedell, Gary M. .
BRAIN INJURY, 2008, 22 (04) :313-324
[33]   Validity of a Pediatric Version of the Glasgow Outcome Scale-Extended [J].
Beers, Sue R. ;
Wisniewski, Stephen R. ;
Garcia-Filion, Pamela ;
Tian, Ye ;
Hahner, Thomas ;
Berger, Rachel P. ;
Bell, Michael J. ;
Adelson, P. David .
JOURNAL OF NEUROTRAUMA, 2012, 29 (06) :1126-1139
[34]   Derangements in blood glucose following initial resuscitation from in-hospital cardiac arrest: A report from the national registry of cardiopulmonary resuscitation [J].
Beiser, David G. ;
Carr, Gordon E. ;
Edelson, Dana P. ;
Peberdy, Mary Ann ;
Hoek, Terry L. Vanden .
RESUSCITATION, 2009, 80 (06) :624-630
[35]   Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest [J].
Bellomo, Rinaldo ;
Bailey, Michael ;
Eastwood, Glenn M. ;
Nichol, Alistair ;
Pilcher, David ;
Hart, Graeme K. ;
Reade, Michael C. ;
Egi, Moritoki ;
Cooper, D. James .
CRITICAL CARE, 2011, 15 (02)
[36]   Plasma Biomarkers of Brain Injury as Diagnostic Tools and Outcome Predictors After Extracorporeal Membrane Oxygenation [J].
Bembea, Melania M. ;
Rizkalla, Nicole ;
Freedy, James ;
Barasch, Noah ;
Vaidya, Dhananjay ;
Pronovost, Peter J. ;
Everett, Allen D. ;
Mueller, Gregory .
CRITICAL CARE MEDICINE, 2015, 43 (10) :2202-2211
[37]   Temperature patterns in the early postresuscitation period after pediatric inhospital cardiac arrest [J].
Bembea, Melania M. ;
Nadkarni, Vinay M. ;
Diener-West, Marie ;
Venugopal, Vidya ;
Carey, Scott M. ;
Berg, Robert A. ;
Hunt, Elizabeth A. .
PEDIATRIC CRITICAL CARE MEDICINE, 2010, 11 (06) :723-730
[38]   Early Oxygenation and Ventilation Measurements After Pediatric Cardiac Arrest: Lack of Association With Outcome [J].
Bennett, Kimberly Statler ;
Clark, Amy E. ;
Meert, Kathleen L. ;
Topjian, Alexis A. ;
Schleien, Charles L. ;
Shaffner, Donald H. ;
Dean, J. Michael ;
Moler, Frank W. .
CRITICAL CARE MEDICINE, 2013, 41 (06) :1534-1542
[39]   Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival [J].
Berg, Robert A. ;
Sutton, Robert M. ;
Reeder, Ron W. ;
Berger, John T. ;
Newth, Christopher J. ;
Carcillo, Joseph A. ;
McQuillen, Patrick S. ;
Meert, Kathleen L. ;
Yates, Andrew R. ;
Harrison, Rick E. ;
Moler, Frank W. ;
Pollack, Murray M. ;
Carpenter, Todd C. ;
Wessel, David L. ;
Jenkins, Tammara L. ;
Notterman, Daniel A. ;
Holubkov, Richard ;
Tamburro, Robert F. ;
Dean, J. Michael ;
Nadkarni, Vinay M. .
CIRCULATION, 2018, 137 (17) :1784-+
[40]   Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs [J].
Berg, Robert A. ;
Nadkarni, Vinay M. ;
Clark, Amy E. ;
Moler, Frank ;
Meert, Kathleen ;
Harrison, Rick E. ;
Newth, Christopher J. L. ;
Sutton, Robert M. ;
Wessel, David L. ;
Berger, John T. ;
Carcillo, Joseph ;
Dalton, Heidi ;
Heidemann, Sabrina ;
Shanley, Thomas P. ;
Zuppa, Athena F. ;
Doctor, Allan ;
Tamburro, Robert F. ;
Jenkins, Tammara L. ;
Dean, J. Michael ;
Holubkov, Richard ;
Pollack, Murray M. .
CRITICAL CARE MEDICINE, 2016, 44 (04) :798-808