Jaks and cytokine receptors - An intimate relationship

[1] Dimerization and activation of the common transducing chain (gp130) of the cytokines of the IL-6 family by mAb [J]. INTERNATIONAL IMMUNOLOGY, 1998, 10 (12) : 1881 - 1889

[2] Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders [J]. LANCET, 2005, 365 (9464) : 1054 - 1061

[3] BEHRMANN I, 2004, J BIOL CHEM 0503

[4] Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog [J]. BLOOD, 2005, 106 (03) : 996 - 1002

[5] Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain [J]. EMBO JOURNAL, 1999, 18 (06) : 1549 - 1558

[6] Crystal structure of the FERM domain of focal adhesion kinase [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (01) : 252 - 259

[7] The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (13) : 6910 - 6915

[8] The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+cell numbers in cynomolgus monkey blood following chronic oral dosing [J]. JOURNAL OF LEUKOCYTE BIOLOGY, 2004, 76 (06) : 1248 - 1255

[9] The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif [J]. MOLECULAR CELL, 2001, 7 (02) : 377 - 385

[10] JAK-STAT SIGNALING INDUCED BY THE V-ABL ONCOGENE [J]. SCIENCE, 1995, 269 (5232) : 1875 - 1877

[1] Dimerization and activation of the common transducing chain (gp130) of the cytokines of the IL-6 family by mAb [J]. INTERNATIONAL IMMUNOLOGY, 1998, 10 (12) : 1881 - 1889

[2] Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders [J]. LANCET, 2005, 365 (9464) : 1054 - 1061

[3] BEHRMANN I, 2004, J BIOL CHEM 0503

[4] Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog [J]. BLOOD, 2005, 106 (03) : 996 - 1002

[5] Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain [J]. EMBO JOURNAL, 1999, 18 (06) : 1549 - 1558

[6] Crystal structure of the FERM domain of focal adhesion kinase [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (01) : 252 - 259

[7] The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (13) : 6910 - 6915

[8] The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+cell numbers in cynomolgus monkey blood following chronic oral dosing [J]. JOURNAL OF LEUKOCYTE BIOLOGY, 2004, 76 (06) : 1248 - 1255

[9] The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif [J]. MOLECULAR CELL, 2001, 7 (02) : 377 - 385

[10] JAK-STAT SIGNALING INDUCED BY THE V-ABL ONCOGENE [J]. SCIENCE, 1995, 269 (5232) : 1875 - 1877