Concomitant myocarditis and painless thyroiditis after AstraZeneca coronavirus disease 2019 vaccination: a case report

被引:5
作者
Marsukjai, Apichai [1 ]
Theerasuwipakorn, Nonthikorn [1 ]
Tumkosit, Monravee [2 ]
Chattranukulchai, Pairoj [1 ]
Srichomkwun, Panudda [3 ,4 ]
Prechawat, Somchai [1 ]
机构
[1] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Cardiac Ctr, Div Cardiovasc Med,Dept Med,Fac Med, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Dept Radiol, Fac Med, Bangkok, Thailand
[3] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Div Endocrinol & Metab, Dept Med,Fac Med, Bangkok, Thailand
[4] King Chulalongkorn Mem Hosp, Excellent Ctr Diabetes, Hormones & Metab, Thai Red Cross Soc, Bangkok, Thailand
关键词
COVID-19; AstraZeneca COVID-19 vaccine; Myocarditis; Thyroiditis; Case report;
D O I
10.1186/s13256-022-03438-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Incidence of myocarditis following messenger RNA coronavirus disease 2019 vaccination has been widely described, but this clinical scenario after adenoviral vector coronavirus disease 2019 vaccination has only been rarely reported. In addition, a few case reports of thyroiditis after adenoviral vector coronavirus disease 2019 vaccination have been published. Case presentation A 55-year-old Thai woman presented with palpitation without neck pain 14 days after receiving AstraZeneca coronavirus disease 2019 vaccination. Electrocardiography revealed sinus tachycardia. Her blood tests showed elevation of cardiac troponin and free triiodothyronine with suppressed serum thyroid stimulating hormone, reflecting a hyperthyroid status. Evidence of myocardial inflammation and necrosis from cardiac magnetic resonance imaging supported the diagnosis of recent myocarditis. Laboratory results and imaging findings were consistent with thyroiditis. After 3 weeks of symptomatic treatment, her symptom and blood tests had returned to normal. Conclusions This case demonstrates that the adenoviral vector coronavirus disease 2019 vaccine could possibly cause myocarditis and painless thyroiditis. Clinicians should have a high index of suspicion and promptly evaluate these conditions, despite minimal symptoms.
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页数:4
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