A versatile and practical synthesis of bis(indolyl)methanes/bis(indolyl)glycoconjugates catalyzed by trichloro-1,3,5-triazine

被引：160

作者：

Sharma, GVM ^{[1
]}

Reddy, JJ ^{[1
]}

Lakshmi, PS ^{[1
]}

Krishna, PR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 3, Discovery Lab, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 41期

关键词：

Bis(indolyl)methanes; aldehydes; sugar aldehydes; electrophilic substitution; trichloro-1,3,5-triazine;

D O I：

10.1016/j.tetlet.2004.08.084

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical and efficient electrophilic substitution reaction of indoles with a variety of aldehydes was carried out using catalytic trichloro-1,3,5-triazine (10mol%,) in acetonitrile to furnish the corresponding bis(indolyl)methanes in excellent yields. Similarly, sugar derived aldehydes gave hitherto unknown bis(indolyl)glycoconjugates in very good yields. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：7729 / 7732

页数：4

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