A versatile and practical synthesis of bis(indolyl)methanes/bis(indolyl)glycoconjugates catalyzed by trichloro-1,3,5-triazine

被引：160
|
作者：
Sharma, GVM [1 ]
Reddy, JJ [1 ]
Lakshmi, PS [1 ]
Krishna, PR [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem 3, Discovery Lab, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 41期
关键词：
Bis(indolyl)methanes; aldehydes; sugar aldehydes; electrophilic substitution; trichloro-1,3,5-triazine;
D O I：
10.1016/j.tetlet.2004.08.084
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A practical and efficient electrophilic substitution reaction of indoles with a variety of aldehydes was carried out using catalytic trichloro-1,3,5-triazine (10mol%,) in acetonitrile to furnish the corresponding bis(indolyl)methanes in excellent yields. Similarly, sugar derived aldehydes gave hitherto unknown bis(indolyl)glycoconjugates in very good yields. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7729 / 7732
页数：4
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