Letter by Molkentin Regarding Article, "The Absence of Evidence Is Not Evidence of Absence: The Pitfalls of Cre Knock-Ins in the c-Kit Locus"

被引：24

作者：

Molkentin, Jeffery D. ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Howard Hughes Med Inst, Dept Pediat, Cincinnati, OH 45229 USA

来源：

CIRCULATION RESEARCH | 2014年 / 115卷 / 08期

关键词：

CARDIAC STEM-CELLS; MAST-CELLS; EXPRESSION; REGENERATION; HEART; GENE; HYPERTROPHY; GROWTH;

D O I：

10.1161/CIRCRESAHA.114.305011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E21 / E23

页数：3

共 17 条

[1] Adult cardiac stem cells are multipotent and support myocardial regeneration [J].

Beltrami, AP ;

Barlucchi, L ;

Torella, D ;

Baker, M ;

Limana, F ;

Chimenti, S ;

Kasahara, H ;

Rota, M ;

Musso, E ;

Urbanek, K ;

Leri, A ;

Kajstura, J ;

Nadal-Ginard, B ;

Anversa, P .

CELL, 2003, 114 (06) :763-776

[2]

Bernex F, 1996, DEVELOPMENT, V122, P3023

[3] A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cells [J].

Berrozpe, Georgina ;

Agosti, Valter ;

Tucker, Christine ;

Blanpain, Cedric ;

Manova, Katia ;

Besmer, Peter .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (15) :5850-5860

[4] Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages [J].

Cairns, LA ;

Moroni, E ;

Levantini, E ;

Giorgetti, A ;

Klinger, FG ;

Tatangelo, L ;

Tiveron, C ;

De Felici, M ;

Dolci, S ;

Magli, MC ;

Giglioni, B ;

Ottolenghi, S .

BLOOD, 2003, 102 (12) :3954-3962

[5] Adult c-kitpos Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair [J].

Ellison, Georgina M. ;

Vicinanza, Carla ;

Smith, Andrew J. ;

Aquila, Iolanda ;

Leone, Angelo ;

Waring, Cheryl D. ;

Henning, Beverley J. ;

Stirparo, Giuliano Giuseppe ;

Papait, Roberto ;

Scarfo, Marzia ;

Agosti, Valter ;

Viglietto, Giuseppe ;

Condorelli, Gianluigi ;

Indolfi, Ciro ;

Ottolenghi, Sergio ;

Torella, Daniele ;

Nadal-Ginard, Bernardo .

CELL, 2013, 154 (04) :827-842

[6] CreERT2 expression from within the c-Kit gene locus allows efficient inducible gene targeting in and ablation of mast cells [J].

Heger, Klaus ;

Seidler, Barbara ;

Vahl, J. Christoph ;

Schwartz, Christian ;

Kober, Maike ;

Klein, Sabine ;

Voehringer, David ;

Saur, Dieter ;

Schmidt-Supprian, Marc .

EUROPEAN JOURNAL OF IMMUNOLOGY, 2014, 44 (01) :296-306

[7] c-Kit-Mediated Functional Positioning of Stem Cells to Their Niches Is Essential for Maintenance and Regeneration of Adult Hematopoiesis [J].

Kimura, Yuki ;

Ding, Bisen ;

Imai, Norikazu ;

Nolan, Daniel J. ;

Butler, Jason M. ;

Rafii, Shahin .

PLOS ONE, 2011, 6 (10)

[8] Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells [J].

Loonstra, A ;

Vooijs, M ;

Beverloo, HB ;

Al Allak, B ;

van Drunen, E ;

Kanaar, R ;

Berns, A ;

Jonkers, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (16) :9209-9214

[9] Adult c-kitpos Cardiac Stem Cells Fulfill Koch's Postulates as Causal Agents for Cardiac Regeneration REPLY [J].

Molkentin, Jeffery D. ;

Houser, Steven R. .

CIRCULATION RESEARCH, 2014, 114 (04) :E27-E27

[10] Are Resident c-Kit+ Cardiac Stem Cells Really All That Are Needed to Mend a Broken Heart? [J].

Molkentin, Jeffery D. ;

Houser, Steven R. .

CIRCULATION RESEARCH, 2013, 113 (09) :1037-1039

← 1 2 →