Evidence-Based Nutritional Advice for Patients Affected by Age-Related Macular Degeneration

被引：12

作者：

Andreatta, Walter ^{[1
]}

El-Sherbiny, Samer ^{[1
]}

机构：

[1] Sandwell & West Birmingham Hosp NHS Trust, Birmingham & Midland Eye Ctr, Birmingham, W Midlands, England

来源：

OPHTHALMOLOGICA | 2014年 / 231卷 / 04期

关键词：

Age-related macular degeneration; Vision; Nutrition; BETA-CAROTENE; COMBINATION; ASSOCIATION; PREVALENCE;

D O I：

10.1159/000357528

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This paper presents the evidence available in the literature on the role of nutrients in preventing the occurrence of age-related macular degeneration (AMD) and its progression to more advanced stages. In our analysis we considered publications on vitamins B, C, E and D, carotenoids (i.e. lutein, zeaxanthin and beta-carotene), Omega-3 polyunsaturated fatty acids and zinc published between 2003 and 2013. While the evidence supporting supplementation and higher dietary intake of nutrients for AMD prevention is weak to moderate, large and robust randomised controlled trials showed that the AREDS formula leads to a 25% reduction in progression to advanced AMD in individuals belonging to AREDS categories 3 and 4. After reviewing the current literature, which includes the AREDS2 study, we suggest an 'evidence-based formula'. (c) 2014 S. Karger AG, Basel

引用

页码：185 / 190

页数：6

共 26 条

[1]

Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group, 1994, N Engl J Med, V330, P1029, DOI 10.1056/NEJM199404143301501

[2]

[Anonymous], COCHRANE DATABASE SY

[3] The role of macular pigment assessment in clinical practice: a review [J].

Bartlett, Hannah ;

Howells, Olivia ;

Eperjesi, Frank .

CLINICAL AND EXPERIMENTAL OPTOMETRY, 2010, 93 (05) :300-308

[4] Macular Pigment Imaging in AREDS2 Participants: An Ancillary Study of AREDS2 Subjects Enrolled at the Moran Eye Center [J].

Bernstein, Paul S. ;

Ahmed, Faisal ;

Liu, Aihua ;

Allman, Susan ;

Sheng, Xiaoming ;

Sharifzadeh, Mohsen ;

Ermakov, Igor ;

Gellermann, Werner .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2012, 53 (10) :6178-6186

[5]

Buring Julie E., 1994, Annals of Epidemiology, V4, P111

[6] Long-Term Effects of Vitamins C and E, β-Carotene, and Zinc on Age-related Macular Degeneration AREDS Report No. 35 [J].

Chew, Emily Y. ;

Clemons, Traci E. ;

Agron, Elvira ;

Sperduto, Robert D. ;

SanGiovanni, John Paul ;

Kurinij, Natalie ;

Davis, Matthew D. .

OPHTHALMOLOGY, 2013, 120 (08) :1604-+

[7] Lutein plus Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial [J].

Chew, Emily Y. ;

Clemons, Traci E. ;

SanGiovanni, John Paul ;

Danis, Ronald ;

Ferris, Frederick L., III ;

Elman, Michael ;

Antoszyk, Andrew ;

Ruby, Alan ;

Orth, David ;

Bressler, Susan ;

Fish, Gary ;

Hubbard, Baker ;

Klein, Michael ;

Chandra, Suresh ;

Blodi, Barbara ;

Domalpally, Amitha ;

Friberg, Thomas ;

Wong, Wai ;

Rosenfeld, Philip ;

Agron, Elvira ;

Toth, Cynthia ;

Bernstein, Paul ;

Sperduto, Robert .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (19) :2005-2015

[8] Fat Consumption and Its Association With Age-Related Macular Degeneration [J].

Chong, Elaine W. -T. ;

Robman, Luibov D. ;

Simpson, Julie A. ;

Hodge, Allison M. ;

Aung, Khin Zaw ;

Dolphin, Theresa K. ;

English, Dallas R. ;

Giles, Graham G. ;

Guymer, Robyn H. .

ARCHIVES OF OPHTHALMOLOGY, 2009, 127 (05) :674-680

[9] Antioxidants and age related eye disease - Current and future perspectives [J].

Christen, WG ;

Glynn, RJ ;

Hennekens, CH .

ANNALS OF EPIDEMIOLOGY, 1996, 6 (01) :60-66

[10] Dietary ω-3 Fatty Acid and Fish Intake and Incident Age-Related Macular Degeneration in Women [J].

Christen, William G. ;

Schaumberg, Debra A. ;

Glynn, Robert J. ;

Buring, Julie E. .

ARCHIVES OF OPHTHALMOLOGY, 2011, 129 (07) :921-929

← 1 2 3 →