Infected Hepatic and Renal Cysts: Differential Impact on Outcome in Autosomal Dominant Polycystic Kidney Disease

被引：30

作者：

Suwabe, Tatsuya ^{[1
]}

Ubara, Yoshifumi ^{[1
]}

Higa, Yasushi ^{[1
]}

Nakanishi, Shohei ^{[1
]}

Sogawa, Yoko ^{[1
]}

Nomura, Kazufumi ^{[1
]}

Nishimura, Hiroaki ^{[1
]}

Hoshino, Jyunichi ^{[1
]}

Sawa, Naoki ^{[1
]}

Katori, Hideyuki ^{[1
]}

Takemoto, Fumi ^{[1
]}

Nakamura, Michio ^{[1
]}

Tomikawa, Shinji ^{[1
]}

Hara, Shigeko ^{[2
]}

Takaichi, Kenmei ^{[1
]}

机构：

[1] Toranomon Gen Hosp, Nephrol Ctr, Tokyo, Japan

[2] Toranomon Gen Hosp, Hlth Care Unit, Tokyo, Japan

来源：

NEPHRON CLINICAL PRACTICE | 2009年 / 112卷 / 03期

关键词：

Infected cysts; Antibiotic therapy; Autosomal dominant polycystic kidney disease; EMBOLIZATION; FLUID; LIVER; THERAPY; PATIENT;

D O I：

10.1159/000214211

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Infected cysts are a frequent and serious complication of autosomal dominant polycystic kidney disease. Such infections are classified into those affecting hepatic cysts and those affecting renal cysts. The purpose of this study was to compare the clinical course of infected hepatic cysts with that of infected renal cysts in patients with autosomal dominant polycystic kidney disease. Methods: We analyzed 43 patients referred to us for additional treatment of severely infected cysts between January 2004 and December 2006. All patients who required further treatment in addition to antibiotic therapy were included. Results: Aspiration was performed in all 28 patients with infected hepatic cysts. As a result, 17 patients were cured, 4 remain under treatment, and 6 died. One patient was cured by partial hepatectomy. Among the 15 patients with renal cysts, aspiration was performed in 4 with identifiable infected cysts, while renal transcatheter arterial embolization after appropriate antibiotic therapy was performed in 11 without identifiable infected cysts. No patient developed recurrence. Conclusion: In patients with infected renal cysts, aspiration or renal transcatheter arterial embolization after appropriate antibiotic therapy was effective. Although aspiration was often effective in patients with infected hepatic cysts, a good outcome was less likely than in those with renal cysts. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：C157 / C163

页数：7

共 21 条

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