Kounis Syndrome secondary to amoxicillin/clavulanic acid use in a child

被引：37

作者：

Biteker, Murat ^{[1
]}

Duran, Niluefer Eksi ^{[1
]}

Biteker, Funda Sungur ^{[2
,3
]}

Erturk, Emre ^{[1
]}

Aykan, Ahmet Cagri ^{[1
]}

Civan, Hasret Ayyildiz ^{[4
]}

Ozkan, Mehmet ^{[1
]}

机构：

[1] Kosuyolu Heart & Res Hosp, Dept Cardiol, Istanbul, Turkey

[2] Kartal Dr Lutfi Kirdar Educ & Res Hosp, Dept Infect Dis, Istanbul, Turkey

[3] Kartal Dr Lutfi Kirdar Educ & Res Hosp, Dept Clin Microbiol, Istanbul, Turkey

[4] Kartal Dr Lutfi Kirdar Educ & Res Hosp, Dept Pediat, Istanbul, Turkey

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2009年 / 136卷 / 01期

关键词：

Kounis Syndrome; Amoxicillin/clavulanic acid; Child; ALLERGIC ANGINA;

D O I：

10.1016/j.ijcard.2008.04.064

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concurrence of acute coronary syndromes with allergic or hypersensitivity as well as with anaphylactic or anaphylactoid reactions is increasingly encountered in clinical practice and there are several reports associating mast cell activation with acute cardiovascular events in adults. It was first described by Kounis as "allergic angina syndrome" progressing to "allergic myocardial infarction". The main mechanism proposed is the vasospasm of coronary arteries. This condition has not been described in childhood. We present a 13-year-old boy, admitted to our hospital with thoracic pain, 30 min after the ingestion of an oral dose of 500 mg of amoxicillin/clavulanic acid. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E3 / E5

页数：3

共 11 条

[1]

Aparci M, 2007, ANADOLU KARDIYOL DER, V7, P343

[2] Mast cells in the development of adaptive immune responses [J].

Galli, SJ ;

Nakae, S ;

Tsai, M .

NATURE IMMUNOLOGY, 2005, 6 (02) :135-142

[3]

KOUNIS NG, 1991, BRIT J CLIN PRACT, V45, P121

[4]

Kounis NG, 1996, CIRCULATION, V94, P1789

[5]

Kounis NG, 1999, CIRCULATION, V100, pE156

[6] Kounis syndrome (allergic angina and allergic myocardial infarction): A natural paradigm? [J].

Kounis, Nicholas G. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2006, 110 (01) :7-14

[7]

López-Abad R, 2004, J INVEST ALLERG CLIN, V14, P162

[8] Acute coronary syndrome due to amoxicillin allergy [J].

Moreno-Ancillo, A ;

Domínguez-Noche, C ;

Gil-Adrados, AC ;

Martín, PMC .

ALLERGY, 2004, 59 (04) :466-+

[9]

Nikolaidis LA, 2002, CAN J CARDIOL, V18, P508

[10] Penicillin allergy in cancer patients manifesting as Kounis syndrome [J].

Soufras, GD ;

Ginopoulos, PV ;

Papadaki, PJ ;

Zavras, GM ;

Gouvelou-Deligianni, GV ;

Batsolaki, M ;

Kouni, S ;

Kounis, NG ;

Koutsojannis, CM .

HEART AND VESSELS, 2005, 20 (04) :159-163

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