Novel polycyclic guanidine alkaloids from two marine sponges of the genus Monanchora

被引：83
作者：
Braekman, JC
Daloze, D
Tavares, R
Hajdu, E
Van Soest, RWM
机构：
[1] Free Univ Brussels, Fac Sci, Dept Organ Chem, Bioorgan Chem Lab, B-1050 Brussels, Belgium
[2] INETI, Dept Tecnol Ind Quim, P-1649038 Lisbon, Portugal
[3] Fed Univ Rio De Janeiro, Dept Invertebrados, Museo Nacl, BR-20940040 Rio De Janeiro, Brazil
[4] Univ Amsterdam, Inst Systemat & Populat Biol, NL-1090 GT Amsterdam, Netherlands
来源：
JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 02期
关键词：
D O I：
10.1021/np990403g
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two marine sponges of the genus Monanchora (Poecilosclerida, Crambeidae) have been found to contain new polycyclic guanidine alkaloids bearing the (5,6,8b)-triazaperhydroacenaphthylene skeleton. Their structures have been determined by detailed spectroscopic analysis. Dehydrobatzelladine C (1) has been isolated from M. arbuscula and crambescidins 359 (2) and 431 (3) from M. unguiculata. The chemotaxonomic implications of these findings are discussed.
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页码：193 / 196
页数：4
相关论文
共 15 条
  • [1] Mirabilins (A-F): New alkaloids from a southern Australian marine sponge, Arenochalina mirabilis
    Barrow, RA
    Murray, LM
    Lim, TK
    Capon, RJ
    [J]. AUSTRALIAN JOURNAL OF CHEMISTRY, 1996, 49 (07) : 767 - 773
  • [2] POLYCYCLIC GUANIDINE ALKALOIDS FROM THE MARINE SPONGE CRAMBE-CRAMBE AND CA++ CHANNEL BLOCKER ACTIVITY OF CRAMBESCIDIN-816
    BERLINCK, RGS
    BRAEKMAN, JC
    DALOZE, D
    BRUNO, I
    RICCIO, R
    FERRI, S
    SPAMPINATO, S
    SPERONI, E
    [J]. JOURNAL OF NATURAL PRODUCTS, 1993, 56 (07): : 1007 - 1015
  • [3] 2 NEW GUANIDINE ALKALOIDS FROM THE MEDITERRANEAN SPONGE CRAMBE-CRAMBE
    BERLINCK, RGS
    BRAEKMAN, JC
    DALOZE, D
    HALLENGA, K
    OTTINGER, R
    BRUNO, I
    RICCIO, R
    [J]. TETRAHEDRON LETTERS, 1990, 31 (45) : 6531 - 6534
  • [4] PTILOCAULIN AND ISOPTILOCAULIN, ANTI-MICROBIAL AND CYTO-TOXIC CYCLIC GUANIDINES FROM THE CARIBBEAN SPONGE PTILOCAULIS AFF P SPICULIFER (LAMARCK, 1814)
    HARBOUR, GC
    TYMIAK, AA
    RINEHART, KL
    SHAW, PD
    HUGHES, RG
    MIZSAK, SA
    COATS, JH
    ZURENKO, GE
    LI, LH
    KUENTZEL, SL
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (18) : 5604 - 5606
  • [5] POLYCYCLIC GUANIDINE-CONTAINING COMPOUNDS FROM THE MEDITERRANEAN SPONGE CRAMBE-CRAMBE - THE STRUCTURE OF 13,14,15-ISOCRAMBESCIDIN 800 AND THE ABSOLUTE STEREOCHEMISTRY OF THE PENTACYCLIC GUANIDINE MOIETIES OF THE CRAMBESCIDINS
    JARESERIJMAN, EA
    INGRUM, AL
    CARNEY, JR
    RINEHART, KL
    SAKAI, R
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (18) : 4805 - 4808
  • [6] CRAMBESCIDINS - NEW ANTIVIRAL AND CYTOTOXIC COMPOUNDS FROM THE SPONGE CRAMBE-CRAMBE
    JARESERIJMAN, EA
    SAKAI, R
    RINEHART, KL
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (19) : 5712 - 5715
  • [7] PTILOMYCALIN-A - A NOVEL POLYCYCLIC GUANIDINE ALKALOID OF MARINE ORIGIN
    KASHMAN, Y
    HIRSH, S
    MCCONNELL, OJ
    OHTANI, I
    KUSUMI, T
    KAKISAWA, H
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (24) : 8925 - 8926
  • [8] PTILOMYCALIN-A, CRAMBESCIDIN-800 AND RELATED NEW HIGHLY CYTOTOXIC GUANIDINE ALKALOIDS FROM THE STARFISHES FROMIA-MONILIS AND CELERINA-HEFFERNANI
    PALAGIANO, E
    DEMARINO, S
    MINALE, L
    RICCIO, R
    ZOLLO, F
    IORIZZI, M
    CARRE, JB
    DEBITUS, C
    LUCARAIN, L
    PROVOST, J
    [J]. TETRAHEDRON, 1995, 51 (12) : 3675 - 3682
  • [9] Three new tricyclic guanidine alkaloids from the sponge Batzella sp.
    Patil, AD
    Freyer, AJ
    Offen, P
    Bean, MF
    Johnson, RK
    [J]. JOURNAL OF NATURAL PRODUCTS, 1997, 60 (07): : 704 - 707
  • [10] NOVEL ALKALOIDS FROM THE SPONGE BATZELLA SP - INHIBITORS OF HIV GP120-HUMAN CD4 BINDING
    PATIL, AD
    KUMAR, NV
    KOKKE, WC
    BEAN, MF
    FREYER, AJ
    DEBROSSE, C
    MAI, S
    TRUNEH, A
    FAULKNER, DJ
    CARTE, B
    BREEN, AL
    HERTZBERG, RP
    JOHNSON, RK
    WESTLEY, JW
    POTTS, BCM
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (05) : 1182 - 1188
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