N-arylpiperidine with axial N-aryl bond. Conformational variation in crystals.

被引：7

作者：

Ogawa, K ^{[1
]}

Harada, J ^{[1
]}

Endo, M ^{[1
]}

Takeuchi, Y ^{[1
]}

Kagawa, H ^{[1
]}

机构：

[1] HITACHI LTD,HITACHI RES LAB,HITACHI,IBARAKI 31912,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(97)01233-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Single crystal X-ray diffraction and C-13 NMR spectroscopic study of two new N-arylpiperidines 4 and 6 reveals that 4 adopts the conformation with the axial N-aryl bond in crystals in contrast to the general tendency of N-arylpiperidines to assume the conformation with an equatorial N-aryl bond. It is shown that the degree of pyramidalization of the nitrogen atom and the orientation of the N-aryl bond are strongly affected by intermolecular interactions in crystals. (C) 1997 Elsevier Science Ltd.

引用

页码：5663 / 5666

页数：4

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