2-Thioindoles as precursors to spiro-fused indolines:: Synthesis of (±)-dehaloperophoramidine

被引：60
|
作者：
Sabahi, Amir [1 ]
Novikov, Alexei [1 ]
Rainier, Jon D. [1 ]
机构：
[1] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 26期
关键词：
communesin; cyclization; natural products; perophoramidine; thioindoles;
D O I：
10.1002/anie.200601278
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Closing the ring: The cyclization of a 2-thioindole with an electrophilic substituent serves as the key transformation in a synthetic strategy for the generation of indole alkaloids of the perophoramidine and communesin class. DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene, Ms = methanesulfonyl chloride. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：4317 / 4320
页数：4
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