Pharmacotherapeutics of SARS-CoV-2 Infections

被引：6

作者：

Kevadiya, Bhavesh D. ^{[1
]}

Machhi, Jatin ^{[1
]}

Herskovitz, Jonathan ^{[1
,2
]}

Oleynikov, Maxim D. ^{[1
]}

Blomberg, Wilson R. ^{[1
]}

Bajwa, Neha ^{[3
]}

Soni, Dhruvkumar ^{[4
]}

Das, Srijanee ^{[1
,2
]}

Hasan, Mahmudul ^{[4
]}

Patel, Milankumar ^{[1
]}

Senan, Ahmed M. ^{[5
]}

Gorantla, Santhi ^{[1
]}

McMillan, JoEllyn ^{[1
]}

Edagwa, Benson ^{[1
]}

Eisenberg, Robert

Gurumurthy, Channabasavaiah B. ^{[1
]}

Reid, St Patrick M. ^{[2
]}

Punyadeera, Chamindie ^{[6
,7
,8
]}

Chang, Linda ^{[9
,10
]}

Gendelman, Howard E. ^{[1
,2
,4
]}

机构：

[1] Univ Nebraska Med Ctr, Coll Med, Dept Pharmacol & Expt Neurosci, Omaha, NE 68198 USA

[2] Univ Nebraska Med Ctr, Coll Med, Dept Pathol & Microbiol, Omaha, NE 68198 USA

[3] Maharaja Ranjit Singh Punjab Tech Univ, Dept Pharmaceut Sci & Technol, Bathinda, PB, India

[4] Univ Nebraska Med Ctr, Coll Pharm, Dept Pharmaceut Sci, Omaha, NE 68198 USA

[5] Nanjing Agr Univ, Coll Food Sci & Technol, Glyc & Glycan Bioengn Res Ctr GGBRC, Nanjing 20095, Peoples R China

[6] Queensland Univ Technol, Sch Biomed Sci, Brisbane, Qld, Australia

[7] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia

[8] Translat Res Inst, Brisbane, Qld, Australia

[9] Univ Maryland, Sch Med, Dept Diagnost Radiol & Nucl Med, Baltimore, MD 21201 USA

[10] Univ Maryland, Sch Med, Dept Neurol, Baltimore, MD 21201 USA

来源：

JOURNAL OF NEUROIMMUNE PHARMACOLOGY | 2021年 / 16卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SARS-CoV-2; COVID-19; therapeutics; Antivirals; Antibodies; Vaccine; EAST RESPIRATORY SYNDROME; CORONAVIRUS; COVID-19; INHIBITORS; ACE2;

D O I：

10.1007/s11481-020-09968-x

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effective treatment options have emerged and now include repurposed antivirals, corticosteroids and virus-specific antibodies. The latter has included convalescence plasma and monoclonal antibodies. Complete viral eradication will be achieved through an effective, safe and preventative vaccine. To now provide a comprehensive summary for each of the pharmacotherapeutics and preventative strategies being offered or soon to be developed for SARS-CoV-2.

引用

页码：12 / 37

页数：26

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