Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy

被引:49
作者
Lee-Sarwar, Kathleen [1 ]
Kelly, Rachel S. [2 ]
Lasky-Su, Jessica [2 ]
Moody, D. Branch [1 ]
Mola, Alex R. [1 ]
Cheng, Tan-Yun [1 ]
Comstock, Laurie E. [3 ,4 ]
Zeiger, Robert S. [5 ]
O'Connor, George T. [6 ,7 ]
Sandel, Megan T. [8 ]
Bacharier, Leonard B. [9 ,10 ]
Beigelman, Avraham [9 ,10 ]
Laranjo, Nancy [2 ]
Gold, Diane R. [2 ,11 ]
Bunyavanich, Supinda [12 ,13 ]
Savage, Jessica H. [1 ]
Weiss, Scott T. [2 ]
Brennan, Patrick J. [1 ]
Litonjua, Augusto A. [2 ]
机构
[1] Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, 75 Francis St, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Div Infect Dis, 75 Francis St, Boston, MA 02115 USA
[4] Harvard Med Sch, Boston, MA USA
[5] Kaiser Permanente Southern Calif, San Diego, CA USA
[6] Boston Univ, Sch Med, Ctr Pulm, Boston, MA 02118 USA
[7] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA
[8] Boston Med Ctr, Dept Pediat, Boston, MA USA
[9] Washington Univ, Sch Med, Dept Pediat, Div Pediat Allergy Immunol & Pulm Med, St Louis, MO 63110 USA
[10] St Louis Childrens Hosp, St Louis, MO 63178 USA
[11] Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA
[12] Icahn Sch Med Mt Sinai, Dept Pediat Allergy Immunol, New York, NY 10029 USA
[13] Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA
基金
美国国家卫生研究院;
关键词
KILLER T-CELLS; VITAMIN-D; ACTIVATION; VARIANTS; PROTEIN; ASTHMA;
D O I
10.1016/j.jaci.2018.04.016
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:335 / +
页数:22
相关论文
共 30 条
  • [1] A method and server for predicting damaging missense mutations
    Adzhubei, Ivan A.
    Schmidt, Steffen
    Peshkin, Leonid
    Ramensky, Vasily E.
    Gerasimova, Anna
    Bork, Peer
    Kondrashov, Alexey S.
    Sunyaev, Shamil R.
    [J]. NATURE METHODS, 2010, 7 (04) : 248 - 249
  • [2] Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface
    Brennan, Patrick J.
    Cheng, Tan-Yun
    Pellicci, Daniel G.
    Watts, Gerald F. M.
    Veerapen, Natacha
    Young, David C.
    Rossjohn, Jamie
    Besra, Gurdyal S.
    Godfrey, Dale I.
    Brenner, Michael B.
    Moody, D. Branch
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (31) : 8348 - 8353
  • [3] Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction
    Brennan, Patrick J.
    Tatituri, Raju V. V.
    Heiss, Christian
    Watts, Gerald F. M.
    Hsu, Fong-Fu
    Veerapen, Natacha
    Cox, Liam R.
    Azadi, Parastoo
    Besra, Gurdyal S.
    Brenner, Michael B.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (37) : 13433 - 13438
  • [4] Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals
    Brennan, Patrick J.
    Tatituri, Raju V. V.
    Brigl, Manfred
    Kim, Edy Y.
    Tuli, Amit
    Sanderson, Joseph P.
    Gadola, Stephan D.
    Hsu, Fong-Fu
    Besra, Gurdyal S.
    Brenner, Michael B.
    [J]. NATURE IMMUNOLOGY, 2011, 12 (12) : 1202 - U97
  • [5] Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota
    Brown, Laura C. Wieland
    Penaranda, Cristina
    Kashyap, Purna C.
    Williams, Brianna B.
    Clardy, Jon
    Kronenberg, Mitchell
    Sonnenburg, Justin L.
    Comstock, Laurie E.
    Bluestone, Jeffrey A.
    Fischbach, Michael A.
    [J]. PLOS BIOLOGY, 2013, 11 (07)
  • [6] QIIME allows analysis of high-throughput community sequencing data
    Caporaso, J. Gregory
    Kuczynski, Justin
    Stombaugh, Jesse
    Bittinger, Kyle
    Bushman, Frederic D.
    Costello, Elizabeth K.
    Fierer, Noah
    Pena, Antonio Gonzalez
    Goodrich, Julia K.
    Gordon, Jeffrey I.
    Huttley, Gavin A.
    Kelley, Scott T.
    Knights, Dan
    Koenig, Jeremy E.
    Ley, Ruth E.
    Lozupone, Catherine A.
    McDonald, Daniel
    Muegge, Brian D.
    Pirrung, Meg
    Reeder, Jens
    Sevinsky, Joel R.
    Tumbaugh, Peter J.
    Walters, William A.
    Widmann, Jeremy
    Yatsunenko, Tanya
    Zaneveld, Jesse
    Knight, Rob
    [J]. NATURE METHODS, 2010, 7 (05) : 335 - 336
  • [7] Evans A. M., 2014, METABOLOMICS, V4, P132, DOI [10.4172/2153-0769.1000132, DOI 10.4172/2153-0769.1000132]
  • [8] Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons
    Haas, Brian J.
    Gevers, Dirk
    Earl, Ashlee M.
    Feldgarden, Mike
    Ward, Doyle V.
    Giannoukos, Georgia
    Ciulla, Dawn
    Tabbaa, Diana
    Highlander, Sarah K.
    Sodergren, Erica
    Methe, Barbara
    DeSantis, Todd Z.
    Petrosino, Joseph F.
    Knight, Rob
    Birren, Bruce W.
    [J]. GENOME RESEARCH, 2011, 21 (03) : 494 - 504
  • [9] Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin
    Jyonouchi, Soma
    Abraham, Valsamma
    Orange, Jordan S.
    Spergel, Jonathan M.
    Gober, Laura
    Dudek, Emily
    Saltzman, Rushani
    Nichols, Kim E.
    Cianferoni, Antonella
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 128 (01) : 102 - U176
  • [10] SPHINGOLIPID COMPOSITION IN BACTEROIDES SPECIES
    KATO, M
    MUTO, Y
    TANAKABANDOH, K
    WATANABE, K
    UENO, K
    [J]. ANAEROBE, 1995, 1 (02) : 135 - 139