Nonlinear optical dye TSQ1 as an efficiently selective fluorescent probe for G-quadruplex DNA

被引：25

作者：

Chen, Yuqi ^{[1
]}

Yan, Shengyong ^{[1
]}

Yuan, Libo ^{[1
]}

Zhou, Yimin ^{[1
]}

Song, Yanyan ^{[1
]}

Xiao, Heng ^{[1
]}

Weng, Xiaocheng ^{[1
]}

Zhou, Xiang ^{[1
,2
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Hubei, Peoples R China

[2] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2014年 / 1卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1039/c3qo00048f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A squarylium dye TSQ1 shows a remarkable fluorescence enhancement selectivity for the G-quadruplex DNA structure against duplex DNA, it can be distinguished even by the naked eye. What is more important, TSQ1 did not induce the G-rich sequence folding into G-quadruplex structure which means TSQ1 can be used to detect G-quadruplex structures in cells.

引用

页码：267 / 270

页数：4

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