Asymmetric autocatalysis induced by meteoritic amino acids with hydrogen isotope chirality

被引：55
作者：
Kawasaki, Tsuneomi [1 ,2 ]
Shimizu, Masako [1 ]
Nishiyama, Daisuke [1 ]
Ito, Masateru [1 ]
Ozawa, Hitomi [1 ]
Soai, Kenso [1 ,2 ]
机构：
[1] Tokyo Univ Sci, Dept Appl Chem, Shinjuku Ku, Tokyo 1628601, Japan
[2] Tokyo Univ Sci, Res Inst Sci & Technol, Shinjuku Ku, Tokyo 1628601, Japan
来源：
CHEMICAL COMMUNICATIONS | 2009年 / 29期
关键词：
HIGHLY ENANTIOSELECTIVE SYNTHESIS; ENANTIOMERIC EXCESS; SYMMETRY-BREAKING; CHROMATOGRAPHIC-SEPARATION; AMPLIFICATION; HOMOCHIRALITY; ORIGIN; ENRICHMENT; AUTOMULTIPLICATION; HYDROCARBONS;
D O I：
10.1039/b908754k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Achiral meteoritic amino acids, glycine and alpha-methylalanine, with hydrogen isotope (D/H) chirality, acted as the source of chirality in asymmetric autocatalysis with amplification of ee to afford highly enantioenriched 5-pyrimidyl alkanols.
引用
收藏
页码：4396 / 4398
页数：3
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