Using generic preference-based measures in mental health: psychometric validity of the EQ-5D and SF-6D

被引:99
作者
Mulhern, Brendan [1 ]
Mukuria, Clara [1 ]
Barkham, Michael [2 ]
Knapp, Martin [3 ,4 ]
Byford, Sarah [3 ]
Soeteman, Djora [5 ]
Brazier, John [1 ]
机构
[1] Univ Sheffield, Sch Hlth & Related Res, Sheffield S1 4DA, S Yorkshire, England
[2] Univ Sheffield, Ctr Psychol Serv Res, Dept Psychol, Sheffield S1 4DA, S Yorkshire, England
[3] Kings Coll London, Ctr Econ Mental & Phys Hlth, London WC2R 2LS, England
[4] Univ London London Sch Econ & Polit Sci, Personal Social Serv Res Unit, London WC2A 2AE, England
[5] Harvard Univ, Sch Publ Hlth, Ctr Hlth Decis Sci, Boston, MA 02115 USA
关键词
COGNITIVE-BEHAVIOR THERAPY; DELIBERATE SELF-HARM; COST-EFFECTIVENESS; SCHIZOPHRENIA; UTILITY; SCALE; DEPRESSION; DISEASE; PEOPLE; BURDEN;
D O I
10.1192/bjp.bp.112.122283
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background Generic preference-based measures (EuroQoL-5D (EQ-5D) and SF-6D) are used in the economic evaluation of mental health interventions. However, there are inconsistent findings regarding their psychometric properties. Aims To investigate the psychometric properties of the EQ-5D and SF-6D in different mental health conditions, using seven existing data-sets. Method The construct validity and responsiveness of the measures were assessed in comparison with condition-specific indicators. Results Evidence for construct validity and responsiveness in common mental health and personality disorders was found (correlations 0.22-0.64; effect sizes 0.37-1.24; standardised response means 0.45-1.31). There was some evidence for validity in schizophrenia (correlations 0.05-0.43), but responsiveness was unclear. Conclusions EQ-5D and SF-6D can be used in the economic evaluation of interventions for common mental health problems with some confidence. In schizophrenia, a preference-based measure focused on the impact of mental health should be considered.
引用
收藏
页码:236 / 243
页数:8
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