Correlates of psychiatric co-morbidity in a sample of Egyptian patients with bipolar disorder

被引:17
作者
Asaad, Tarek [1 ]
Okasha, Tarek [1 ]
Ramy, Hisham [1 ]
Fekry, Mohamed [1 ]
Zaki, Nivert [1 ]
Azzam, Hanan [1 ]
Rabie, Menan AbdelMaksoud [1 ]
Elghoneimy, Soheir [1 ]
Sultan, Marwa [1 ]
Hamed, Hani [2 ]
Refaat, Osama [2 ]
Shorab, Iman [1 ]
Elhabiby, Mahmoud [1 ]
Elgweily, Tamer [2 ]
ElShinnawy, Hanan [2 ]
Nasr, Mohamed [2 ]
Fathy, Heba [2 ]
Meguid, Marwa A. [1 ]
Nader, Doaa [1 ]
Elserafi, Doha [1 ]
Enaba, Dalia [2 ]
Ibrahim, Dina [1 ]
Elmissiry, Marwa [1 ]
Mohsen, Nesreen [1 ]
Ahmed, Sherin [1 ]
机构
[1] Ain Shams Univ, Inst Psychiat, Cairo, Egypt
[2] Cairo Univ, Inst Psychiat, Cairo, Egypt
关键词
Bipolar disorder; Comorbidity; Substance abuse; Anxiety disorders; SUBSTANCE USE DISORDERS; ANXIETY DISORDERS; COMORBIDITY; PREVALENCE; IMPAIRMENT; SYMPTOMS; LIFETIME; IMPACT;
D O I
10.1016/j.jad.2014.04.050
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and objectives: Bipolar disorder (BD) is a complex, chronic mood disorder involving repeated episodes of depression and mania/hypomania. Two thirds of patients with bipolar disorder have a comorbid psychiatric condition. This study aims to assess the prevalence of Axis l diagnosis with its socio-demographic and clinical correlates among a sample of Egyptian patients with bipolar disorder. Methods: Out of the 400 patients who were enrolled in the study from number of governmental and private psychiatric hospitals in Cairo, Egypt, 350 patients diagnosed with bipolar affective disorders (157 females and 193 males) with age ranging from 18 to 55 years were selected. Patients were assessed using the Structured Clinical Interview for DSM-IV Axis I disorder (Research Version) (SCID-I). Results: Prevalence of psychiatric comorbidity among ED patients was 20.3% (71 patients) among which 63 patients (18%) had comorbid substance abuse and 8 patients (2.3%) had comorbid anxiety disorders. Limitations: The study was limited by its cross sectional design with some patients having florid symptoms during assessment, not having a well representative community sample. This might have decreased the reliability and prevalence of lifetime psychiatric comorbidity due to uncooperativeness or memory bias. The study group was composed of bipolar patients attending tertiary care service which limits the possibility of generalizing these results on different treatment settings. Conclusions: Substance abuse followed by anxiety disorders was found to be the most common psychiatric comorbidity. Family history of psychiatric disorders and substance abuse as well as current psychotic features were highly correlated with comorbidity. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:347 / 352
页数:6
相关论文
共 36 条
[11]   The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issues [J].
Freeman, MP ;
Freeman, SA ;
McElroy, SL .
JOURNAL OF AFFECTIVE DISORDERS, 2002, 68 (01) :1-23
[12]  
GITLIN MJ, 1995, AM J PSYCHIAT, V152, P1635
[13]   Co-morbid anxiety disorders in bipolar disorder and major depression: familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder [J].
Goes, F. S. ;
McCusker, M. G. ;
Bienvenu, O. J. ;
MacKinnon, D. F. ;
Mondimore, F. M. ;
Schweizer, B. ;
DePaulo, J. R., Jr. ;
Potash, J. B. .
PSYCHOLOGICAL MEDICINE, 2012, 42 (07) :1449-1459
[14]   The role of age in the development of Schneiderian symptoms in patients with a first psychotic episode [J].
González-Pinto, A ;
van Os, J ;
Peralta, V ;
de Heredia, JLP ;
Mosquera, F ;
Aldama, A ;
González, C ;
Gutiérrez, M ;
Micó, JA .
ACTA PSYCHIATRICA SCANDINAVICA, 2004, 109 (04) :264-268
[15]   Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders - Results from the national epidemiologic survey on alcohol and related conditions [J].
Grant, BF ;
Stinson, FS ;
Dawson, DA ;
Chou, SP ;
Dufour, MC ;
Compton, W ;
Pickering, RP ;
Kaplan, K .
ARCHIVES OF GENERAL PSYCHIATRY, 2004, 61 (08) :807-816
[16]  
HARROW M, 1990, ARCH GEN PSYCHIAT, V47, P665
[17]   Customization in prescribing for bipolar disorder [J].
Hodgkin, Dominic ;
Volpe-Vartanian, Joanna ;
Merrick, Elizabeth L. ;
Horgan, Constance M. ;
Nierenberg, Andrew A. ;
Frank, Richard G. ;
Lee, Sue .
HEALTH ECONOMICS, 2012, 21 (06) :653-668
[18]   Psychosocial Functioning, Familiality, and Psychiatric Comorbidity in Bipolar Youth With and Without Psychotic Features [J].
Hua, Liwei L. ;
Wilens, Timothy E. ;
Martelon, Mary Kate ;
Wong, Patricia ;
Wozniak, Janet ;
Biederman, Joseph .
JOURNAL OF CLINICAL PSYCHIATRY, 2011, 72 (03) :397-405
[19]   Presence of co-morbid substance use disorder in bipolar patients worsens their social functioning to the level observed in patients with schizophrenia [J].
Jaworski, Fabienne ;
Dubertret, Caroline ;
Ades, Jean ;
Gorwood, Philip .
PSYCHIATRY RESEARCH, 2011, 185 (1-2) :129-134
[20]  
Keller M. B., 2006, J CLIN PSYCHIAT S1, V67, pS5