Conjugated Photosensitizers for Imaging and PDT in Cancer Research

被引:104
作者
Simoes, Joao C. S. [1 ,2 ]
Sarpaki, Sophia [2 ]
Papadimitroulas, Panagiotis [2 ]
Therrien, Bruno [1 ]
Loudos, George [2 ]
机构
[1] Univ Neuchatel, Inst Chem, CH-2000 Neuchatel, Switzerland
[2] BioEmiss Technol Solut, Athens 11472, Greece
关键词
POSITRON-EMISSION-TOMOGRAPHY; MESOPOROUS SILICA NANOPARTICLES; TARGETED PHOTODYNAMIC THERAPY; HYALURONIC-ACID NANOPARTICLES; IRON-OXIDE NANOPARTICLES; GROWTH-FACTOR RECEPTOR; CU-64-ATSM IN-VITRO; DRUG-DELIVERY; TUMOR HYPOXIA; QUANTUM DOTS;
D O I
10.1021/acs.jmedchem.0c00047
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Early cancer detection and perfect understanding of the disease are imperative toward efficient treatments. It is straightforward that, for choosing a specific cancer treatment methodology, diagnostic agents undertake a critical role. Imaging is an extremely intriguing tool since it assumes a follow up to treatments to survey the accomplishment of the treatment and to recognize any conceivable repeating injuries. It also permits analysis of the disease, as well as to pursue treatment and monitor the possible changes that happen on the tumor. Likewise, it allows screening the adequacy of treatment and visualizing the state of the tumor. Additionally, when the treatment is finished, observing the patient is imperative to evaluate the treatment methodology and adjust the treatment if necessary. The goal of this review is to present an overview of conjugated photosensitizers for imaging and therapy.
引用
收藏
页码:14119 / 14150
页数:32
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