The trace copper and zine in lymphocytes among normal people in Keshan non-Keshan disease areas, or those with latent and chronic Keshan disease were determined by FAAS with sample-added curve technique. The method is simple, rapid with good precision and accuracy, and eliminates the interference effectively.,The correlation coefficients of Cu and Zn were 1.000 0 and 0.999 2, respectively. The relative standard deriations were 2.3%-6.4% and the rate of recoveries were 93%-104%. The results showed: Cu level had no difference among 4 groups, Zn level increased in those with latent and chronic Keshan disease. The Zn/Cu value of normal people in increased in those with latent and chronic Keshan disease. The Zn/Cu value of normal people in Keshan disease areas and those with latent and chronic Keshan disease also increased.