A Comprehensive Review on Function of miR-15b-5p in Malignant and Non-Malignant Disorders

被引：27
作者：
Ghafouri-Fard, Soudeh [1 ]
Khoshbakht, Tayyebeh [2 ]
Hussen, Bashdar Mahmud [3 ,4 ]
Jamal, Hazha Hadayat [5 ]
Taheri, Mohammad [6 ,7 ]
Hajiesmaeili, Mohammadreza [8 ,9 ]
机构：
[1] Shahid Beheshti Univ Med Sci, Sch Med, Dept Med Genet, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Mens Hlth & Reprod Hlth Res Ctr, Tehran, Iran
[3] Hawler Med Univ, Coll Pharm, Dept Pharmacognosy, Erbil, Iraq
[4] Lebanese French Univ, Ctr Res, Strateg Studies, Erbil, Iraq
[5] Salahaddin Univ, Coll Educ, Dept Biol, Erbil, Iraq
[6] Shahid Beheshti Univ Med Sci, Urol & Nephrol Res Ctr, Tehran, Iran
[7] Jena Univ Hosp, Inst Human Genet, Jena, Germany
[8] Shahid Beheshti Univ Med Sci, Loghman Hakim Hosp, Skull Base Res Ctr, Tehran, Iran
[9] Shahid Beheshti Univ Med Sci, Loghman Hakim Hosp, Dept Anesthesiol, Tehran, Iran
来源：
FRONTIERS IN ONCOLOGY | 2022年 / 12卷
关键词：
miR-15b-5p; cancer; biomarker; expression; malignance; ENDOPLASMIC-RETICULUM STRESS; CANCER METASTASIS; APOPTOSIS; INJURY; CELLS; CARCINOMA; TUMORIGENICITY; EXPRESSION; BIOMARKERS; PROTECTS;
D O I：
10.3389/fonc.2022.870996
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
miR-15b-5p is encoded by MIR15B gene. This gene is located on cytogenetic band 3q25.33. This miRNA participates in the pathogenesis of several cancers as well as non-malignant conditions, such as abdominal aortic aneurysm, Alzheimer's and Parkinson's diseases, cerebral ischemia reperfusion injury, coronary artery disease, dexamethasone induced steatosis, diabetic complications and doxorubicin-induced cardiotoxicity. In malignant conditions, both oncogenic and tumor suppressor impacts have been described for miR-15b-5p. Dysregulation of miR-15b-5p in clinical samples has been associated with poor outcome in different kinds of cancers. In this review, we discuss the role of miR-15b-5p in malignant and non-malignant conditions.
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页数：14
相关论文
共 75 条
[41]   Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer's disease [J].
Poursaei, Elham ;
Abolghasemi, Mahsa ;
Bornehdeli, Soghra ;
Shanehbandi, Dariush ;
Asadi, Milad ;
Sadeghzadeh, Mahsa ;
Rahmanpour, Dara ;
Sadeh, Reza Naghdi .
PSYCHIATRIC GENETICS, 2022, 32 (01) :25-29
[42]   Staphylococcus aureus Triggers Induction of miR-15B-5P to Diminish DNA Repair and Deregulate Inflammatory Response in Diabetic Foot Ulcers [J].
Ramirez, Horacio A. ;
Pastar, Irena ;
Jozic, Ivan ;
Stojadinovic, Olivera ;
Stone, Rivka C. ;
Ojeh, Nkemcho ;
Gil, Joel ;
Davis, Stephen C. ;
Kirsner, Robert S. ;
Tomic-Canic, Marjana .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018, 138 (05) :1187-1196
[43]  
Salimi S, 2019, IRAN J ALLERGY ASTHM, V18, P332, DOI 10.18502/ijaai.v18i3.1126
[44]   Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2 [J].
Sato, Akira ;
Ogino, Yoko ;
Tanuma, Sei-ichi ;
Uchiumi, Fumiaki .
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2021, 40 (08) :790-797
[45]   High Glucose-Induced Apoptosis in Human Kidney Cells Was Alleviated by miR-15b-5p Mimics [J].
Shen, Hua ;
Fang, Kaikai ;
Guo, Haifeng ;
Wang, Guojun .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2019, 42 (05) :758-763
[46]   Hydrogen sulfide of air induces macrophage extracellular traps to aggravate inflammatory injury via the regulation of miR-15b-5p on MAPK and insulin signals in trachea of chickens [J].
Song, Nuan ;
Wang, Wei ;
Wang, Yue ;
Guan, Yalin ;
Xu, Shiwen ;
Guo, Meng-Yao .
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 771
[47]   RETRACTED: Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs (Retracted article. See vol. 16, pg. 745, 2023) [J].
Sun, Feng ;
Wu, Ke ;
Yao, Zhixian ;
Mu, Xingyu ;
Zheng, Zhong ;
Sun, Menghao ;
Wang, Yong ;
Liu, Zhihong ;
Zhu, Yiyong .
ONCOTARGETS AND THERAPY, 2020, 13 :6755-6765
[48]   SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p [J].
Sun, Li-Na ;
Zhi, Zheng ;
Chen, Liang-Yan ;
Zhou, Qun ;
Li, Xiu-Ming ;
Gan, Wen-Juan ;
Chen, Shu ;
Yang, Meng ;
Liu, Yao ;
Shen, Tong ;
Xu, Yong ;
Li, Jian-Ming .
CANCER LETTERS, 2017, 409 :104-115
[49]   IL-6 Genomic Variants and Risk of Prostate Cancer [J].
Taheri, Mohammad ;
Noroozi, Rezvan ;
Rakhshan, Azadeh ;
Ghanbari, Molud ;
Omrani, Mir Davood ;
Ghafouri-Fard, Soudeh .
UROLOGY JOURNAL, 2019, 16 (05) :463-468
[50]   Plasma miR-15b-5p and miR-590-5p for distinguishing patients with bladder cancer from healthy individuals [J].
Toelle, Angelika ;
Buckendahl, Laura ;
Jung, Klaus .
ONCOLOGY REPORTS, 2019, 42 (04) :1609-1620
12345678