Structured histopathology for endotyping and planning rational treatment in chronic rhinosinusitis

被引:24
作者
Brescia, Giuseppe [1 ]
Alessandrini, Lara [2 ]
Marioni, Gino [1 ]
机构
[1] Padova Univ, Otolaryngol Sect, Dept Neurosci DNS, Via Giustiniani 2, I-35128 Padua, Italy
[2] Padova Univ, Dept Med DIMED, Padua, Italy
关键词
Chronic rhinosinusitis; Structured histopathology; Endotypes; Nasal polyps; Biologics; EOSINOPHIL; POLYPS; AIRWAY;
D O I
10.1016/j.amjoto.2020.102795
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
In chronic rhinosinusitis (CRS), endotyping, being based on the pathogenic mechanism, provides a precise picture appropriate for use in clinical practice. Structured histopathological examination of CRS is considered a necessary step in efforts to establish its pathogenesis and improve our endotyping capabilities. Herein we discuss the associations between histopathology and clinical characteristics of CRS patients to assist medical and surgical treatment choices.
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页数:5
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