Structured histopathology for endotyping and planning rational treatment in chronic rhinosinusitis

被引:24
作者
Brescia, Giuseppe [1 ]
Alessandrini, Lara [2 ]
Marioni, Gino [1 ]
机构
[1] Padova Univ, Otolaryngol Sect, Dept Neurosci DNS, Via Giustiniani 2, I-35128 Padua, Italy
[2] Padova Univ, Dept Med DIMED, Padua, Italy
关键词
Chronic rhinosinusitis; Structured histopathology; Endotypes; Nasal polyps; Biologics; EOSINOPHIL; POLYPS; AIRWAY;
D O I
10.1016/j.amjoto.2020.102795
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
In chronic rhinosinusitis (CRS), endotyping, being based on the pathogenic mechanism, provides a precise picture appropriate for use in clinical practice. Structured histopathological examination of CRS is considered a necessary step in efforts to establish its pathogenesis and improve our endotyping capabilities. Herein we discuss the associations between histopathology and clinical characteristics of CRS patients to assist medical and surgical treatment choices.
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页数:5
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共 34 条
[1]   Epithelial cell function and remodeling in nasal polyposis [J].
Bankova, Lora G. ;
Barrett, Nora A. .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2020, 124 (04) :333-341
[2]   Remodeling changes of the upper airway with chronic rhinosinusitis [J].
Barham, Henry P. ;
Osborn, Jodi L. ;
Snidvongs, Kornkiat ;
Mrad, Nadine ;
Sacks, Raymond ;
Harvey, Richard J. .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2015, 5 (07) :565-572
[3]   Treatment of rhinosinusitis and histopathology of nasal mucosa: A controlled, randomized, clinical study [J].
Bizaki, Argyro J. ;
Numminen, Jura ;
Taulu, Rami ;
Kholova, Ivana ;
Rautiainen, Markus .
LARYNGOSCOPE, 2016, 126 (12) :2652-2658
[4]   EOSINOPHILIC INFLAMMATION IN ASTHMA [J].
BOUSQUET, J ;
CHANEZ, P ;
LACOSTE, JY ;
BARNEON, G ;
GHAVANIAN, N ;
ENANDER, I ;
VENGE, P ;
AHLSTEDT, S ;
SIMONYLAFONTAINE, J ;
GODARD, P ;
MICHEL, FB .
NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (15) :1033-1039
[5]   Prognostic role of blood eosinophil and basophil levels in allergic fungal rhinosinusitis (AFRS) [J].
Brescia, Giuseppe ;
Franz, Leonardo ;
Alessandrini, Lara ;
Parrino, Daniela ;
Barion, Umberto ;
Marioni, Gino .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2020, 41 (01)
[6]   Emerging Contribution of Histopathology to Our Understanding of Chronic Rhinosinusitis Endotypes: Tissue Eosinophil Count and Aggregates [J].
Brescia, Giuseppe ;
Alessandrini, Lara ;
Parrino, Daniela ;
Franz, Leonardo ;
Barion, Umberto ;
Marioni, Gino .
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2020, 34 (01) :122-126
[7]   A classification of chronic rhinosinusitis with nasal polyps based on structured histopathology [J].
Brescia, Giuseppe ;
Alessandrini, Lara ;
Giacomelli, Luciano ;
Parrino, Daniela ;
Zanotti, Claudia ;
Tealdo, Giulia ;
Franz, Leonardo ;
Carraro, Valentina ;
Barion, Umberto ;
Marioni, Gino .
HISTOPATHOLOGY, 2020, 76 (02) :296-307
[8]   No Differences in Nasal Tissue Inflammatory Cells and Adhesion Molecules (iCAM-1 and vCAM-1) Based on the Comparison of EGPA With Eosinophilic Chronic Sinusitis With Polyposis [J].
Brescia, Giuseppe ;
Schiavon, Franco ;
Nicole, Lorenzo ;
Zanoletti, Elisabetta ;
Zanotti, Claudia ;
Padoan, Roberto ;
Felicetti, Mara ;
Parrino, Daniela ;
Cinetto, Francesco ;
Cangiano, Daniela ;
Giacomelli, Luciano ;
Cappellesso, Rocco ;
Martini, Alessandro ;
Fassina, Ambrogio ;
Marioni, Gino .
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2019, 33 (04) :395-402
[9]   Histopathological and hematological changes in recurrent nasal polyposis [J].
Brescia, Giuseppe ;
Alessandrini, Lara ;
Zanotti, Claudia ;
Parrino, Daniela ;
Tealdo, Giulia ;
Torsello, Miriam ;
Zybine, Vladislav ;
Giacomelli, Luciano ;
Barion, Umberto ;
Marioni, Gino .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2019, 9 (07) :813-820
[10]   Nasal polyposis pathophysiology: Endotype and phenotype open issues [J].
Brescia, Giuseppe ;
Zanotti, Claudia ;
Parrino, Daniela ;
Barion, Umberto ;
Marioni, Gino .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2018, 39 (04) :441-444