Eculizumab for Atypical Hemolytic-Uremic Syndrome.

被引:278
作者
Nuernberger, Jens [1 ]
Witzke, Oliver [1 ]
Saez, Anabelle Opazo [1 ]
Vester, Udo [1 ]
Baba, Hideo Andreas [1 ]
Kribben, Andreas [1 ]
Zimmerhackl, Lothar Bernd [2 ]
Janecke, Andreas R. [2 ]
Nagel, Mato [3 ]
Kirschfink, Michael [4 ]
机构
[1] Univ Duisburg Essen, D-45122 Essen, Germany
[2] Innsbruck Med Univ, A-6020 Innsbruck, Austria
[3] Ctr Nephrol & Metab Disorders, D-02943 Weisswasser, Germany
[4] Univ Heidelberg, D-69120 Heidelberg, Germany
关键词
D O I
10.1056/NEJMc0808527
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:542 / 544
页数:3
相关论文
共 5 条
[1]  
ARICETA G, 2008, PEDIAT NEPHROL 0918
[2]   Mechanisms of Disease: the complement system in renal injury - new ways of looking at an old foe [J].
Brown, Katherine M. ;
Sacks, Steven H. ;
Sheerin, Neil S. .
NATURE CLINICAL PRACTICE NEPHROLOGY, 2007, 3 (05) :277-286
[3]   Genetics of HUS:: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome [J].
Caprioli, Jessica ;
Noris, Marina ;
Brioschi, Simona ;
Pianetti, Gaia ;
Castelletti, Federica ;
Bettinaglio, Paola ;
Mele, Caterina ;
Bresin, Elena ;
Cassis, Linda ;
Gamba, Sara ;
Porrati, Francesca ;
Bucchioni, Sara ;
Monteferrante, Giuseppe ;
Fang, Celia J. ;
Liszewski, M. K. ;
Kavanagh, David ;
Atkinson, John P. ;
Remuzzi, Giuseppe .
BLOOD, 2006, 108 (04) :1267-1279
[4]   Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria [J].
Hillmen, P ;
Hall, C ;
Marsh, JCW ;
Elebute, M ;
Bombara, MP ;
Petro, BE ;
Cullen, MJ ;
Richards, SJ ;
Rollins, SA ;
Mojcik, CF ;
Rother, RP .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (06) :552-559
[5]   Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome [J].
Zipfel, Peter F. ;
Edey, Matthew ;
Heinen, Stefan ;
Jozsi, Mihaly ;
Richter, Heiko ;
Misselwitz, Joachim ;
Hoppe, Bernd ;
Routledge, Danny ;
Strain, Lisa ;
Hughes, Anne E. ;
Goodship, Judith A. ;
Licht, Christoph ;
Goodship, Timothy H. J. ;
Skerka, Christine .
PLOS GENETICS, 2007, 3 (03) :387-392