Industrialization of Quantitative Systems Pharmacology

被引：1

作者：

Topp, Brian ^{[1
]}

Trujillo, Maria E. ^{[1
]}

Sinha, Vikram ^{[1
]}

机构：

[1] Merck & Co Inc, Merck Res Labs, Quantitat Pharmacol & Pharmacometr, Pharmacokinet Pharmacodynam & Drug Metab, Kenilworth, NJ 07033 USA

来源：

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY | 2019年 / 8卷 / 06期

关键词：

MODEL;

D O I：

10.1002/psp4.12427

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

As a result of our limited understanding of human pathophysiology, many drugs never become medicines. The use of quantitative systems pharmacology (QSP) has seen many advances with the goal of improving the probability of technical success. Many research and development (R&D) organizations have invested in QSP models; however, areas that require continuous efforts are best practices, training, education, and the clear understanding of regulatory expectations.

引用

收藏

页码：356 / 358

页数：3

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