The complete mitochondrial genome of the Mongolian gerbil, Meriones unguiculatus (Rodentia: Muridae: Gerbillinae)

被引:7
作者
Kim, Eun Bae [1 ,2 ]
Lee, Sang-Goo [1 ,3 ]
机构
[1] Ewha Womans Univ, Dept Bioinspired Sci, Seoul, South Korea
[2] Kangwon Natl Univ, Dept Anim Life Sci, Chunchon 200701, South Korea
[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Genet,Dept Med, Boston, MA 02115 USA
关键词
Epilepsy; Meriones unguiculatu; mitogenome; Mongolian gerbil; TRANSFER RNALYS; MUTATION; EPILEPSY;
D O I
10.3109/19401736.2014.953091
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The complete mitochondrial genome of the Mongolian gerbil, Meriones unguiculatus, was sequenced. The 16,360bp long genome has 37 genes typical for rodent mitogenomes, including 22 tRNA genes, 2 rRNA genes, and 13 protein-coding genes. The total GC content of the mitochondrial genome is 36.96% with the base composition of 32.61% A, 23.71% C, 13.24% G, and 30.44% T. Translational terminators of three genes (cytb, cox3, and nad4) were generated by the addition of 3 A residues to the mRNA. This novel rodent mitochondrial genome will provide comparable information for understanding the rodent mitochondrial evolution.
引用
收藏
页码:1457 / 1458
页数:2
相关论文
共 6 条
[1]   THE MONGOLIAN GERBIL IN EXPERIMENTAL EPILEPSY [J].
BERTORELLI, R ;
ADAMI, M ;
ONGINI, E .
ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1995, 16 (1-2) :101-106
[2]   The role of mitochondria in aging [J].
Bratic, Ana ;
Larsson, Nils-Goran .
JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (03) :951-957
[3]   A novel de novo mutation of the mitochondrial tRNAlys gene mt.8340G>A associated with pure myopathy [J].
Jeppesen, Tina Dysgaard ;
Duno, Morten ;
Risom, Lotte ;
Wibrand, Flemming ;
Rafiq, Jabin ;
Krag, Thomas ;
Jakobsen, Johannes ;
Andersen, Henning ;
Vissing, John .
NEUROMUSCULAR DISORDERS, 2014, 24 (02) :162-166
[4]   MYOCLONIC EPILEPSY AND RAGGED-RED FIBER DISEASE (MERRF) IS ASSOCIATED WITH A MITOCHONDRIAL-DNA TRANSFER RNALYS MUTATION [J].
SHOFFNER, JM ;
LOTT, MT ;
LEZZA, AMS ;
SEIBEL, P ;
BALLINGER, SW ;
WALLACE, DC .
CELL, 1990, 61 (06) :931-937
[5]   Automatic annotation of organellar genomes with DOGMA [J].
Wyman, SK ;
Jansen, RK ;
Boore, JL .
BIOINFORMATICS, 2004, 20 (17) :3252-3255
[6]  
YONEDA M, 1990, BIOCHEM INT, V21, P789