Langerhans cell histiocytosis (LCH) is a rare disease characterised by monoclonal proliferation and infiltration of organs by large mononuclear cells. Organs commonly involved include the lungs and pituitary gland. However, the disease association with hypogonadotrophic hypogonadism has not been reported in the literature, to our knowledge. We report a 26-year-old Chinese man with LCH, recurrent pneumothoraces, diabetes insipidus and hypogonadotrophic hypogonadism. The clinical features and management of the disease are reviewed.
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Osped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Montefusco, L.
Harari, S.
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Osped San Giuseppe Multimed, Serv Fisiopatol Resp & Emodinam Polmonare, UO Pneumol & Terapia Semiintens Resp, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Harari, S.
Elia, D.
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Osped San Giuseppe Multimed, Serv Fisiopatol Resp & Emodinam Polmonare, UO Pneumol & Terapia Semiintens Resp, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Elia, D.
Rossi, A.
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Osped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Rossi, A.
Specchia, C.
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Univ Brescia, Dipartimento Med Mol & Traslaz, Brescia, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Specchia, C.
Torre, O.
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Osped San Giuseppe Multimed, Serv Fisiopatol Resp & Emodinam Polmonare, UO Pneumol & Terapia Semiintens Resp, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Torre, O.
Adda, G.
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Osped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy
Adda, G.
Arosio, M.
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Univ Milan, Dipartimento Sci Cli & Comunita, Fdn IRCCS Ca Granda Osped Maggiore Policlin, UO Endocrinol, Milan, ItalyOsped San Giuseppe Multimed, UO Malattie Endocrine & Diabetol, Milan, Italy