Grade 3 Lymphomatoid Granulomatosis in a Patient Receiving Methotrexate Therapy for Rheumatoid Arthritis

被引：13

作者：

Oiwa, Hiroshi ^{[1
]}

Mihara, Keichiro ^{[2
]}

Kan, Takanobu ^{[3
]}

Tanaka, Maiko ^{[3
]}

Shindo, Hajime ^{[3
]}

Kumagai, Kazuhiko ^{[1
]}

Sugiyama, Eiji ^{[1
]}

机构：

[1] Hiroshima Univ Hosp, Dept Clin Immunol & Rheumatol, Hiroshima, Japan

[2] Hiroshima Univ, Dept Hematol & Oncol, Res Inst Radiat Biol & Med, Hiroshima 730, Japan

[3] Hiroshima Univ, Hiroshima Univ Hosp, Dept Dermatol, Hiroshima 730, Japan

来源：

INTERNAL MEDICINE | 2014年 / 53卷 / 16期

关键词：

lymphomatoid granulomatosis; methotrexate (MTX); rheumatoid arthritis;

D O I：

10.2169/internalmedicine.53.2593

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

引用

页码：1873 / 1875

页数：3

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