Synthesis and Biological Activities of Novel Substituted Pyrazole Oximes Containing Substituted Pyridine Group

In order to explore novel potent pesticide from pyrazole oxime derivatives, a series of new pyrazole oxime ester compounds bearing substituted pyridine moiety were synthesized by the introduction of pyridyl backbone into the molecules of pyrazole oxime. Their structures were confirmed by H-1 NMR, C-13 NMR and elemental analysis. Preliminary bioassay results showed that some of the title compounds displayed certain insecticidal and acaricidal activities. For example, compound Si exhibited insecticidal activity against Aphis craccivora with 90% mortality at the concentration of 400 mu g/mL.