Reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions

被引：20

作者：

Aborways, Marwa M. ^{[1
]}

Moran, Wesley J. ^{[1
]}

机构：

[1] Univ Huddersfield, Dept Chem, Huddersfield HD1 3DH, W Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 13期

关键词：

Halogenation; Propargyl alcohols; Oxidation; Synthesis; BROMINATION; ACID; ALKYNES; EFFICIENT; KETONES;

D O I：

10.1016/j.tetlet.2014.02.042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The study of the reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions is presented. With sodium iodide, alpha-iodoenones were formed, however, with sodium bromide or chloride the alpha-haloenones were only formed in low yields under anhydrous conditions. Conversely, upon addition of water to the reaction mixtures, alpha,alpha-dibromoketones and alpha,alpha-dichloroketones were formed in good yields, but alpha,alpha-diiodoketones were not observed. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：2127 / 2129

页数：3

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