Recent research trends of radio-frequency biosensors for biomolecular detection

被引:45
作者
Lee, Hee-Jo [1 ]
Yook, Jong-Gwan [1 ]
机构
[1] Yonsei Univ, Sch Elect & Elect Engn, Seoul 120749, South Korea
关键词
Biosensor; Biomolecule; Diagnosis; Radio-frequency; Detectable limit; LABEL-FREE DETECTION; CARBON NANOTUBES; GRAPHENE; RF; FUNCTIONALIZATION; RESONATOR; GLUCOSE; SENSORS; NMR;
D O I
10.1016/j.bios.2014.05.025
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
This article reviews radio-frequency (RF) biosensors based on passive and/or active devices and circuits. In particular, we focus on RF biosensors designed for detection of various biomolecules such as biotin-streptavidin, DNA hybridization, IgG, and glucose. The performance of these biosensors has been enhanced by the introduction of various sensing schemes with diverse nanomaterials (e.g., carbon nanotubes, graphene oxide, magnetic and gold nanoparticles, etc.). In addition, the RF biosensing platforms that can be associated with an RF active system are discussed. Finally, the challenges of RF biosensors are presented and suggestions are made for their future direction and prospects. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:448 / 459
页数:12
相关论文
共 54 条
[1]  
[Anonymous], 2004, MICROWAVE ELECT MEAS
[2]   Comparative advantages of mechanical biosensors [J].
Arlett, J. L. ;
Myers, E. B. ;
Roukes, M. L. .
NATURE NANOTECHNOLOGY, 2011, 6 (04) :203-215
[3]   A label-free immunosensor array using single-chain antibody fragments [J].
Backmann, N ;
Zahnd, C ;
Huber, F ;
Bietsch, A ;
Plückthun, A ;
Lang, HP ;
Güntherodt, HJ ;
Hegner, M ;
Gerber, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (41) :14587-14592
[4]   Microwaving Blood as a Non-Destructive Technique for Haemoglobin Measurements on Microlitre Samples [J].
Basey-Fisher, Toby H. ;
Guerra, Nadia ;
Triulzi, Chiara ;
Gregory, Andrew ;
Hanham, Stephen M. ;
Stevens, Molly M. ;
Maier, Stefan A. ;
Klein, Norbert .
ADVANCED HEALTHCARE MATERIALS, 2014, 3 (04) :536-542
[5]   BioMEMS: state-of-the-art in detection, opportunities and prospects [J].
Bashir, R .
ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (11) :1565-1586
[6]   Ultrafast and sensitive bioassay using split ring resonator structures and microwave heating [J].
Caglayan, Humeyra ;
Cakmakyapan, Semih ;
Addae, Sarah A. ;
Pinard, Melissa A. ;
Caliskan, Deniz ;
Aslan, Kadir ;
Ozbay, Ekmel .
APPLIED PHYSICS LETTERS, 2010, 97 (09)
[7]   Quartz crystal microbalance study of DNA immobilization and hybridization for nucleic acid sensor development [J].
Caruso, F ;
Rodda, E ;
Furlong, DF ;
Niikura, K ;
Okahata, Y .
ANALYTICAL CHEMISTRY, 1997, 69 (11) :2043-2049
[8]   Mediated biosensors [J].
Chaubey, A ;
Malhotra, BD .
BIOSENSORS & BIOELECTRONICS, 2002, 17 (6-7) :441-456
[9]   Detection of biomolecular surface interactions by transit time measurements with a coplanar transmission line probe [J].
Chen, Qin ;
Roitman, Daniel ;
Knoesen, Andre .
SENSORS AND ACTUATORS A-PHYSICAL, 2009, 152 (02) :151-159
[10]   Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors [J].
Chen, RJ ;
Bangsaruntip, S ;
Drouvalakis, KA ;
Kam, NWS ;
Shim, M ;
Li, YM ;
Kim, W ;
Utz, PJ ;
Dai, HJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) :4984-4989