Improving efficacy and reducing toxicity of anti-PD-L1 treatment: T-cells as delivery vehicles for anti-PD-L1 blocking nanobodies

被引:0
|
作者
Petit, P-F. [1 ]
Zhu, J. [1 ]
van den Eynde, B. J. [1 ]
机构
[1] Ludwig Inst Canc Res, De Duve Inst, Brussels, Belgium
关键词
D O I
10.1016/j.annonc.2020.10.511
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
25P
引用
收藏
页码:S1425 / S1425
页数:1
相关论文
共 50 条
  • [31] Dynamic Changes of Plasma PD-L1 mRNA Expression Predict Response to Anti-PD-1/Anti-PD-L1 Treatment in Malignancies
    Sun, J.
    Yang, Q.
    Chen, M.
    Gu, J.
    Zheng, L.
    Yu, Y.
    Li, F.
    Zhang, L.
    Niu, K.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S451 - S451
  • [32] ANTI-PD-1 AND ANTI-PD-L1 ANTIBODIES AS IMMUNOTHERAPY AGAINST CANCER: A STRUCTURAL PERSPECTIVE
    Cordova-Bahena, Luis
    Velasco-Velazquez, Marco A.
    REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, 2021, 73 (01): : 8 - 16
  • [33] Anti-PD-1 and Anti-PD-L1 Monoclonal Antibodies in People Living with HIV and Cancer
    Kathryn Lurain
    Ramya Ramaswami
    Robert Yarchoan
    Thomas S. Uldrick
    Current HIV/AIDS Reports, 2020, 17 : 547 - 556
  • [34] Anti-PD-1 and Anti-PD-L1 Monoclonal Antibodies in People Living with HIV and Cancer
    Lurain, Kathryn
    Ramaswami, Ramya
    Yarchoan, Robert
    Uldrick, Thomas S.
    CURRENT HIV/AIDS REPORTS, 2020, 17 (05) : 547 - 556
  • [35] Hair Repigmentation With Anti-PD-1 and Anti-PD-L1 Immunotherapy: A Novel Hypothesis Reply
    Rivera, Noelia
    Boada, Aram
    Ferrandiz, Carlos
    JAMA DERMATOLOGY, 2018, 154 (01) : 113 - 114
  • [36] Anti-PD-1/Anti-PD-L1 Drugs and Radiation Therapy: Combinations and Optimization Strategies
    Boustani, Jihane
    Lecoester, Benoit
    Baude, Jeremy
    Latour, Charlene
    Adotevi, Olivier
    Mirjolet, Celine
    Truc, Gilles
    CANCERS, 2021, 13 (19)
  • [37] Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1 /PD-1 immunotherapy
    Ioannou, Nikolaos
    Hagner, Patrick R.
    Stokes, Matt
    Gandhi, Anita K.
    Apollonio, Benedetta
    Fanous, Mariam
    Papazoglou, Despoina
    Sutton, Lesley-Ann
    Rosenquist, Richard
    Amini, Rose-Marie
    Chiu, Hsiling
    Lopez-Girona, Antonia
    Janardhanan, Preethi
    Awan, Farrukh T.
    Jones, Jeffrey
    Kay, Neil E.
    Shanafelt, Tait D.
    Tallman, Martin S.
    Stamatopoulos, Kostas
    Patten, Piers E. M.
    Vardi, Anna
    Ramsay, Alan G.
    BLOOD, 2021, 137 (02) : 216 - 231
  • [38] Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection
    Balsitis, Scott
    Gali, Volodymyr
    Mason, Pamela J.
    Chaniewski, Susan
    Levine, Steven M.
    Wichroski, Michael J.
    Feulner, Michael
    Song, Yunling
    Granaldi, Karen
    Loy, James K.
    Thompson, Chris M.
    Lesniak, Jacob A.
    Brockus, Catherine
    Kishnani, Narendra
    Menne, Stephan
    Cockett, Mark I.
    Iyer, Renuka
    Mason, Stephen W.
    Tenney, Daniel J.
    PLOS ONE, 2018, 13 (02):
  • [39] Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)
    Kowanetz, Marcin
    Zou, Wei
    Gettinger, Scott N.
    Koeppen, Hartmut
    Kockx, Mark
    Schmid, Peter
    Kadel, Edward E., III
    Wistuba, Ignacio
    Chaft, Jamie
    Rizvi, Naiyer A.
    Spigel, David R.
    Spira, Alexander
    Hirsch, Fred R.
    Cohen, Victor
    Smith, Dustin
    Boyd, Zach
    Miley, Natasha
    Flynn, Susan
    Leveque, Vincent
    Shames, David S.
    Ballinger, Marcus
    Mocci, Simonetta
    Shankar, Geetha
    Funke, Roel
    Hampton, Garret
    Sandler, Alan
    Amler, Lukas
    Mellman, Ira
    Chen, Daniel S.
    Hegde, Priti S.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (43) : E10119 - E10126
  • [40] Metformin facilitates anti-PD-L1 efficacy through the regulation of intestinal microbiota
    Zhao, Xiaopeng
    Liu, Chuang
    Peng, Licheng
    Wang, Hongyan
    GENES AND IMMUNITY, 2024, 25 (01) : 7 - 13