Host cell targets for African swine fever virus

被引：23

作者：

Munoz-Moreno, Raquel ^{[1
]}

Galindo, Inmaculada ^{[1
]}

Angel Cuesta-Geijo, Miguel ^{[1
]}

Barrado-Gil, Lucia ^{[1
]}

Alonso, Covadonga ^{[1
]}

机构：

[1] Inst Nacl Invest & Tecnol Agr & Alimentaria INIA, Dept Biotechnol, Madrid 28040, Spain

来源：

VIRUS RESEARCH | 2015年 / 209卷

关键词：

African swine fever virus; Virus entry; Endocytosis; Host cell targets; Cholesterol; Phosphatidylinositol phosphates and kinases; Aggresomes; HDAC6; BAG3; Viral factories; HERPES-SIMPLEX-VIRUS; ENDOPLASMIC-RETICULUM; ASSEMBLY SITES; PROTEIN P54; DEPENDENT ENDOCYTOSIS; SELECTIVE AUTOPHAGY; NUCLEOTIDE-SEQUENCE; AGGRESOME FORMATION; RUSSIAN-FEDERATION; ATTACHMENT PROTEIN;

D O I：

10.1016/j.virusres.2015.05.026

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Viruses are strict intracellular pathogens that require the cellular environment to complete a successful infection. Among them, African swine fever virus (ASFV) is an evolutionary ancient DNA virus, endemic in Africa, which is nowadays causing an emergent disease in Europe with a potential high economic impact in the pig industry. It is well known that host-cell components are critical crossroads mapping the virus path for a productive infection, some of them at the endocytic pathway. Considering that ASFV infectious cycle strongly relies in several factors from the host cell, the study of virus host interactions remains crucial as they will reveal the obstacles, routes and tracks, hints and the target waypoint in the virus journey to destination. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：118 / 127

页数：10

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