Management of chemotherapy-induced alopecia (CIA): A comprehensive review and future directions

被引：13
作者：
Haque, Emaan [1 ]
Alabdaljabar, Mohamad S. [1 ]
Ruddy, Kathryn J. [2 ]
Haddad, Tufia C. [2 ]
Thompson, Carrie A. [3 ]
Lehman, Julia S. [4 ]
Hashmi, Shahrukh K. [3 ,5 ]
机构：
[1] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia
[2] Mayo Clin, Div Med Oncol, Rochester, MN USA
[3] Mayo Clin, Div Hematol, Dept Med, 200 1st St SW, Rochester, MN 55905 USA
[4] Mayo Clin, Dept Dermatol & Lab Med, Rochester, MN USA
[5] Mayo Clin, Sheikh Shakhbout Med City, Abu Dhabi, U Arab Emirates
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2020年 / 156卷
关键词：
Chemotherapy; Alopecia; Hair-loss; QUALITY-OF-LIFE; BREAST-CANCER PATIENTS; DOXORUBICIN-INDUCED ALOPECIA; SCALP COOLING DEVICE; ADJUVANT CHEMOTHERAPY; BODY-IMAGE; HAIR LOSS; ANDROGENETIC ALOPECIA; PATIENT PERCEPTIONS; PERMANENT ALOPECIA;
D O I：
10.1016/j.critrevonc.2020.103093
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Objectives: To review and summarize the available literature on the management of chemotherapy-induced alopecia (CIA) including complementary and alternative medicine (CAM), and to present CIA's effect on quality of life (QoL). Methods: Nine databases were searched for CIA-related keywords, including the effect on QoL, and management options. Among 1019 articles found, 54 articles focusing on treatment/prevention or QoL were retrieved. References of selected articles were also checked manually. Results: CIA was found to negatively affect QoL and body image, regardless of head covering status (i.e., for cultural or religious reasons). Most studies related to treatment/prevention of CIA reported on the use of scalp-cooling. The efficacy of CAM treatments was found to be questionable. Conclusion: A high incidence rate of CIA exists with certain chemotherapies, and it significantly impairs QoL. Preventive and treatment strategies are incompletely effective. Additional literature is needed to explore potential preventive or therapeutic options for CIA.
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页数：13
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