The paediatric burden of rotavirus disease in Europe

被引:81
作者
Banyai, Krisztian [1 ]
Desselberger, Ulrich [1 ]
Franco, Elisabetta [1 ]
Giaquinto, Carlo [1 ]
Grimprel, Emmanuel [1 ]
Huppertz, Hans-Ko [1 ]
Mezsner, Zsofia [1 ]
Mrukowicz, Jacek [1 ]
Rodrigo, Carlos [1 ]
Soriano-Gabarro, Montse [1 ]
Tatochenko, Vladimir [1 ]
Vesikari, Timo [1 ]
De Vos, Beatrice [1 ]
Wolleswinkel-van den Bosch, Judith [1 ]
机构
[1] Dipartimento Pediat, I-35128 Padua, Italy
关键词
D O I
10.1017/S0950268806006091
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Rotaviruses are a major cause of hospitalizations for acute gastroenteritis in developed countries. This review shows the burden of rotavirus disease in < 5-year-old children in Europe. An estimated 72 000-77 000 hospitalizations for community-acquired rotavirus disease occur annually in the 23 million under-fives living in the European Union (EU-25), with a median cost of E1417 per case. Annual hospitalization incidence rates range from 0(.)3 to 11(.)9/1000 children < 5 years old (median 3/1000). The median proportion of hospital-acquired rotavirus disease among all cases of hospitalization for rotavirus disease is estimated to be 21%. Countries of the EU-25 require information on the burden of rotavirus disease to support introduction of rotavirus vaccines. Data on cases treated at home, medical visits, and emergency wards as well as rotavirus-associated deaths are limited. To fully evaluate the impact and effectiveness of rotavirus vaccination programmes in Europe, additional epidemiological studies will be critical and desirable.
引用
收藏
页码:908 / 916
页数:9
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