A review on the effects of Allium sativum (Garlic) in metabolic syndrome

被引:117
作者
Hosseini, A. [1 ]
Hosseinzadeh, H. [2 ]
机构
[1] Mashhad Univ Med Sci, Pharmacol Res Ctr Med Plants, Sch Med, Mashhad, Iran
[2] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynam & Toxicol, Pharmaceut Res Ctr, Mashhad, Iran
关键词
Garlic; Allium sativum; Metabolic syndrome; Cardiovascular disease; Hypertension; Diabetes; Dyslipidemia; Obesity; REDUCES BLOOD-PRESSURE; LIPID-METABOLISM; POWDER TABLETS; SERUM-LIPIDS; CARDIOVASCULAR RISK; OXIDATIVE STRESS; DIABETIC-NEPHROPATHY; EXTRACT CONSUMPTION; ANTIFUNGAL ACTIVITY; DIALLYL DISULFIDE;
D O I
10.1007/s40618-015-0313-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The metabolic syndrome is a common problem world-wide and includes abdominal obesity, hypertension, dyslipidemia, and hyperglycemia disorders. It leads to insulin resistance and the development of diabetes mellitus or cardiovascular disease. Allium sativum (garlic) has been documented to exhibit anti-diabetic, hypotensive, and hypolipidemic properties. This suggests a potential role of A. sativum in the management of metabolic syndrome; however, more studies should be conducted to evaluate its effectiveness. In this review, we discussed the most relevant articles to find out the role of A. sativum in different components of metabolic syndrome and cardiovascular disease risk factors. Because human reports are rare, further studies are required to establish the clinical value of A. sativum in metabolic syndrome.
引用
收藏
页码:1147 / 1157
页数:11
相关论文
共 130 条
  • [51] Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in Renal Transplant Recipients
    Jabbari A.
    Argani H.
    Ghorbanihaghjo A.
    Mahdavi R.
    [J]. Lipids in Health and Disease, 4 (1)
  • [52] JAIN RC, 1975, ARTERY, V1, P115
  • [53] EFFECT OF GARLIC ON SERUM-LIPIDS, COAGULABILITY AND FIBRINOLYTIC-ACTIVITY OF BLOOD
    JAIN, RC
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1977, 30 (09) : 1380 - 1381
  • [54] Jawaria Younas Jawaria Younas, 2014, International Journal of Chemical and Biochemical Sciences, V5, P22
  • [55] Anti-obesity effects of hot water extract and high hydrostatic pressure extract of garlic in rats fed a high-fat diet
    Joo, Hyunjin
    Kim, Chong-Tai
    Kim, In-Hwan
    Kim, Yangha
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2013, 55 : 100 - 105
  • [56] KAMANNA VS, 1984, INDIAN J MED RES, V79, P580
  • [57] EFFECT OF GARLIC (ALLIUM-SATIVUM LINN) ON SERUM-LIPOPROTEINS AND LIPOPROTEIN CHOLESTEROL LEVELS IN ALBINO-RATS RENDERED HYPER-CHOLESTEREMIC BY FEEDING CHOLESTEROL
    KAMANNA, VS
    CHANDRASEKHARA, N
    [J]. LIPIDS, 1982, 17 (07) : 483 - 488
  • [58] Hepatic mechanisms of the Walnut antidiabetic effect in mice
    Kamyab, Hanieh
    Hejrati, Shohreh
    Khanavi, Mahnaz
    Malihi, Farshad
    Mohammadirad, Azadeh
    Baeeri, Maryam
    Esmaily, Hadi
    Abdollahi, Mohammad
    [J]. CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 2010, 5 (03): : 304 - 309
  • [59] Attenuation of streptozotocin-induced oxidative stress in hepatic and intestinal tissues of wistar rat by methanolic-garlic extract
    Kanth, V. Rajani
    Reddy, P. Uma Maheswara
    Raju, T. N.
    [J]. ACTA DIABETOLOGICA, 2008, 45 (04) : 243 - 251
  • [60] Metabolic syndrome: definitions and controversies
    Kassi, Eva
    Pervanidou, Panagiota
    Kaltsas, Gregory
    Chrousos, George
    [J]. BMC MEDICINE, 2011, 9