Langerhans cell histiocytosis associated with partial DiGeorge syndrome in a newborn

被引：2
作者：
LevendogluTugal, O
Noto, R
Juster, F
Brudnicki, A
Slim, M
Beneck, D
Jayabose, S
机构：
[1] NEW YORK MED COLL,DEPT PEDIAT SURG,VALHALLA,NY 10595
[2] WESTCHESTER CTY MED CTR,DEPT RADIOL,VALHALLA,NY 10595
[3] WESTCHESTER CTY MED CTR,DEPT PATHOL,VALHALLA,NY 10595
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 1996年 / 18卷 / 04期
关键词：
Langerhans cell histiocytosis; DiGeorge syndrome; Newborn infant;
D O I：
10.1097/00043426-199611000-00014
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: We report the unrecognized association of Langerhans cell histiocytosis (LCH) with partial DiGeorge syndrome. Patient and Methods: A 7-week-old infant with endocrine and immunologic characteristics of DiGeorge syndrome displayed multisystem involvement of Letterer-Siwe disease at birth. Results: Despite vigorous medical support and chemotherapy, she died at 9 months of age with multisystem failure. Conclusion: This case supports the role of the thymus in the pathogenesis of LCH.
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收藏
页码：401 / 404
页数：4
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