A Cross-sectional Survey Assessing Carriage of Streptococcus pneumoniae in a Healthy Population in Xinjiang Uygur Autonomous Region of China

被引：4

作者：

Xie Na ^{[1
,2
,3
]}

Chen Zhao Yun ^{[4
]}

Chen Tao ^{[3
]}

Zhu Bing Qing ^{[2
]}

Xu Li ^{[2
]}

Gao Yuan ^{[2
]}

Zhang Ai Yu ^{[2
]}

Zhao Pan ^{[2
]}

Liu Ji Wen ^{[1
]}

Shao Zhu Jun ^{[2
,5
]}

机构：

[1] Xinjiang Med Univ, Dept Publ Hlth, Urumqi 830054, Xinjiang, Peoples R China

[2] Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Natl Inst Communicable Dis Control & Prevent, Beijing 102206, Peoples R China

[3] Ctr Dis Control & Prevent Xinjiang Uygur Autonomo, Urumqi 830011, Xinjiang, Peoples R China

[4] Xinjiang Med Univ, Affiliated Hosp 1, Med Lab Ctr, Urumqi 830054, Xinjiang, Peoples R China

[5] Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou 310058, Zhejiang, Peoples R China

来源：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES | 2018年 / 31卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Cross-sectional survey; Streptococcus pneumoniae carriage; Real-time PCR; Xinjiang; China;

D O I：

10.3967/bes2018.029

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The carriage rate and serotype distribution of Streptococcus pneumoniae (S. pneumoniae) in a healthy population in China remains unclear. In this study, we collected the oropharyngeal swabs from 513 individuals in Xinjiang, China. Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S. pneumoniae carriage. The total carriage rate of S. pneumoniae was 70.4% (361/513). The most prevalent serotypes were 19B/F, 18B/C, 5, and 6A/B. The highest carriage rate of S. pneumoniae was noted in children aged 6-10 years (88.6%), which merits further attention. The co-colonization rate of two or more S. pneumoniae serotypes was 79.8% (264/331). This study aimed to investigate the baseline pneumococcal carriage rate among healthy individuals in China to improve our understanding of the epidemiology of S. pneumoniae.

引用

页码：233 / +

页数：6

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