The Mechanism of Physical Activity-induced Amelioration of Parkinson's Disease: A Narrative Review

被引:15
作者
Gronek, Piotr [1 ]
Haas, Aline Nogueira [2 ]
Czarny, Wojciech [3 ]
Podstawski, Robert [4 ]
Delabary, Marcela do Santos [2 ]
Clark, Cain C. T. [5 ]
Boraczynski, Michal [6 ]
Tarnas, Maria [1 ]
Wycichowska, Paulina [1 ]
Pawlaczyk, Mariola [7 ]
Gronek, Joanna [1 ]
机构
[1] Poznan Univ Phys Educ, Dept Hlth Sci, Lab Genet, Poznan, Poland
[2] Univ Fed Rio Grande do Sul, Sch Phys Educ Physiotherapy & Dance, Porto Alegre, RS, Brazil
[3] Univ Rzeszow, Dept Human Sci, Rzeszow, Poland
[4] Univ Warmia & Mazury, Dept Tourism Recreat & Ecol, Olsztyn, Poland
[5] Coventry Univ, Fac Hlth & Life Sci, Coventry, W Midlands, England
[6] Univ Warmia & Mazury, Publ Hlth, Olsztyn, Poland
[7] Poznan Univ Med Sci, Dept Geriatr Med & Gerontol, Poznan, Poland
来源
AGING AND DISEASE | 2021年 / 12卷 / 01期
关键词
Parkinson disease; physical activity; motor symptoms; cognitive networks; mind-body interventions; RANDOMIZED CONTROLLED-TRIAL; QUALITY-OF-LIFE; TAI CHI; AEROBIC EXERCISE; DEFAULT NETWORK; HEALTH-BENEFITS; BALANCE CONTROL; DANCE PROGRAM; BRAIN HEALTH; MUTATIONS;
D O I
10.14336/AD.2020.0407
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Physical activity, together with its ameliorative effects on Parkinson's disease (PD) symptoms, remains a relatively unappreciated factor which may be beneficial for the treatment outcome. Contemporary evidence supports the positive effects of non-pharmacological approaches to PD symptom management, in particular the effects of the exercise on both, motor and non-motor symptoms. The aim of the study was to review the mechanisms of exercise-induced amelioration of PD symptoms. Methods: Electronic databases (PubMed, Web of Science and Google Scholar) were searched using the following key words: "Parkinson and physical activity" OR "Parkinson disease and exercise" OR "Parkinson disease and lifestyle factors" OR "Parkinson disease and longevity". A total of 97 studies which investigated PD genetics and various forms of exercise and their etiologic impact on PD were reviewed. The studies were subdivided into four topic groups: 1) genetics of PD, 2) exercise and the brain, 3) physical activity and PD, 4) mind-body interventions, and discussed accordingly. Adequate levels of physical activity are associated with higher quality of life in PD patients. Physical activity may have protective and stimulatory effects for better functional efficiency in higher-level cognitive networks. It can also improve balance and motor functions by improving muscle strength. Given the etiologic evidence of the beneficial effects of physical activity on PD, albeit tentative, a concerted effort to elucidate the processes and outcomes of physical activity on ameliorating symptoms of PD must be undertaken.
引用
收藏
页码:192 / 202
页数:11
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