The type III secretion signal of Yersinia enterocolitica YopN was mapped using a gene fusion approach. yopN codons 1 to 12 were identified as critical for signal function. Several synonymous mutations that abolish secretion of hybrid proteins without altering the codon specificity of yopN mRNA were identified.
机构:
Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
Lee, VT
Schneewind, O
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Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
机构:
Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
Lee, VT
Mazmanian, SK
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Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
Mazmanian, SK
Schneewind, O
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Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
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Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
Cheng, LW
Schneewind, O
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Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
机构:
German Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, GermanyGerman Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, Germany
Buettner, Carina
Niemann, Hartmut
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German Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, GermanyGerman Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, Germany
Niemann, Hartmut
Heinz, Dirk
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German Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, GermanyGerman Res Ctr Biotechnol GBF, Div Struct Biol, D-38124 Braunschweig, Germany