Surface modification for DNA and protein microarrays

被引：47

作者：

Oh, Soon Jin ^{[1
]}

Hong, Bong Jin

Choi, Kwan Yong

Park, Joon Won

机构：

[1] Konkuk Univ, Inst Biomed Sci & Technol, Dept Biomed Sci & Technol, Seoul 143701, South Korea

[2] Pohang Univ Sci & Technol, NSB Postech, Pohang, South Korea

[3] Pohang Univ Sci & Technol, Bionanotechnol Ctr, Pohang, South Korea

来源：

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY | 2006年 / 10卷 / 03期

关键词：

D O I：

10.1089/omi.2006.10.327

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Microarrays of biomolecules are emerging as powerful tools for genomics, proteomics, and clinical assays, since they make it possible to screen biologically important binding events in a parallel and high throughput fashion. Because the microarrays are fabricated on a solid support, coating of the surface and immobilization strategy of the biomolecules are major issues for successful microarray fabrication. This review deals with both DNA microarrays and protein microarrays, and focuses on the various modification approaches for the two-dimensional surface materials and three-dimensional ones. In addition, the immobilization strategies including adsorption, covalent attachment, physical entrapment, and affinity attachment of the biomolecules are summarized, and advantage and limitation of representative efforts are discussed.

引用

页码：327 / 343

页数：17

共 170 条

[51]

Haab BB, 2001, GENOME BIOL, V2

[52] Grafting of polypeptides on solid substrates by initiation of N-carboxyanhydride polymerization by amino-terminated self-assembled monolayers [J].

Heise, A ;

Menzel, H ;

Yim, H ;

Foster, MD ;

Wieringa, RH ;

Schouten, AJ ;

Erb, V ;

Stamm, M .

LANGMUIR, 1997, 13 (04) :723-728

[53] Mixed silane self assembled monolayers and their in situ modification [J].

Heise, A ;

Stamm, M ;

Rauscher, M ;

Duschner, H ;

Menzel, H .

THIN SOLID FILMS, 1998, 327 :199-203

[54] Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices [J].

Henry, AC ;

Tutt, TJ ;

Galloway, M ;

Davidson, YY ;

McWhorter, CS ;

Soper, SA ;

McCarley, RL .

ANALYTICAL CHEMISTRY, 2000, 72 (21) :5331-5337

[55] Characterization of DNA probes immobilized on gold surfaces [J].

Herne, TM ;

Tarlov, MJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (38) :8916-8920

[56] Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments [J].

Herwig, R ;

Aanstad, P ;

Clark, M ;

Lehrach, H .

NUCLEIC ACIDS RESEARCH, 2001, 29 (23)

[57] Zwitterionic SAMs that resist nonspecific adsorption of protein from aqueous buffer [J].

Holmlin, RE ;

Chen, XX ;

Chapman, RG ;

Takayama, S ;

Whitesides, GM .

LANGMUIR, 2001, 17 (09) :2841-2850

[58] Nanoscale-controlled spacing provides DNA microarrays with the SNP discrimination efficiency in solution phase [J].

Hong, BJ ;

Oh, SJ ;

Youn, TO ;

Kwon, SH ;

Park, JW .

LANGMUIR, 2005, 21 (10) :4257-4261

[59] DNA microarrays on nanoscale-controlled surface [J].

Hong, BJ ;

Sunkara, V ;

Park, JW .

NUCLEIC ACIDS RESEARCH, 2005, 33 (12) :1-8

[60] Self-assembly of a dendron through multiple ionic interaction to give mesospacing between reactive amine groups on the surface [J].

Hong, BJ ;

Shim, JY ;

Oh, SJ ;

Park, JW .

LANGMUIR, 2003, 19 (06) :2357-2365

← 1 2 3 4 5 6 7 8 9 10 →