Surface modification for DNA and protein microarrays

被引：47

作者：

Oh, Soon Jin ^{[1
]}

Hong, Bong Jin

Choi, Kwan Yong

Park, Joon Won

机构：

[1] Konkuk Univ, Inst Biomed Sci & Technol, Dept Biomed Sci & Technol, Seoul 143701, South Korea

[2] Pohang Univ Sci & Technol, NSB Postech, Pohang, South Korea

[3] Pohang Univ Sci & Technol, Bionanotechnol Ctr, Pohang, South Korea

来源：

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY | 2006年 / 10卷 / 03期

关键词：

D O I：

10.1089/omi.2006.10.327

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Microarrays of biomolecules are emerging as powerful tools for genomics, proteomics, and clinical assays, since they make it possible to screen biologically important binding events in a parallel and high throughput fashion. Because the microarrays are fabricated on a solid support, coating of the surface and immobilization strategy of the biomolecules are major issues for successful microarray fabrication. This review deals with both DNA microarrays and protein microarrays, and focuses on the various modification approaches for the two-dimensional surface materials and three-dimensional ones. In addition, the immobilization strategies including adsorption, covalent attachment, physical entrapment, and affinity attachment of the biomolecules are summarized, and advantage and limitation of representative efforts are discussed.

引用

页码：327 / 343

页数：17

共 170 条

[1] Preparation of DNA and protein micro arrays on glass slides coated with an agarose film [J].

Afanassiev, Victor ;

Hanemann, Vera ;

Woelfl, Stefan .

NUCLEIC ACIDS RESEARCH, 2000, 28 (12) :E66

[2] Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible [J].

Amano, K ;

Leung, PSC ;

Xu, QC ;

Marik, J ;

Quan, C ;

Kurth, MJ ;

Nantz, MH ;

Ansari, AA ;

Lam, KS ;

Zeniya, M ;

Coppel, RL ;

Gershwin, ME .

JOURNAL OF IMMUNOLOGY, 2004, 172 (10) :6444-6452

[3] Next generation of protein microarray support materials:: Evaluation for protein and antibody microarray applications [J].

Angenendt, P ;

Glökler, J ;

Sobek, J ;

Lehrach, H ;

Cahill, DJ .

JOURNAL OF CHROMATOGRAPHY A, 2003, 1009 (1-2) :97-104

[4] Toward optimized antibody microarrays:: a comparison of current microarray support materials [J].

Angenendt, P ;

Glökler, J ;

Murphy, D ;

Lehrach, H ;

Cahill, DJ .

ANALYTICAL BIOCHEMISTRY, 2002, 309 (02) :253-260

[5] Protein microchips: Use for immunoassay and enzymatic reactions [J].

Arenkov, P ;

Kukhtin, A ;

Gemmell, A ;

Voloshchuk, S ;

Chupeeva, V ;

Mirzabekov, A .

ANALYTICAL BIOCHEMISTRY, 2000, 278 (02) :123-131

[6] A comparison of gel-based, nylon filter and microarray techniques to detect differential RNA expression in plants [J].

Baldwin, D ;

Crane, V ;

Rice, D .

CURRENT OPINION IN PLANT BIOLOGY, 1999, 2 (02) :96-103

[7] Versatile derivatisation of solid support media for covalent bonding on DNA-microchips [J].

Beier, M ;

Hoheisel, JD .

NUCLEIC ACIDS RESEARCH, 1999, 27 (09) :1970-1977

[8] Quantitative assessment of factors affecting the sensitivity of a competitive immunomicroarray for pesticide detection [J].

Belleville, E ;

Dufva, M ;

Aamand, J ;

Bruun, L ;

Christensen, CBV .

BIOTECHNIQUES, 2003, 35 (05) :1044-+

[9] DNA microarrays based on noncovalent oligonucleotide attachment and hybridization in two dimensions [J].

Belosludtsev, Y ;

Iverson, B ;

Lemeshko, S ;

Eggers, R ;

Wiese, R ;

Lee, S ;

Powdrill, T ;

Hogan, M .

ANALYTICAL BIOCHEMISTRY, 2001, 292 (02) :250-256

[10] DNA microarrays with PAMAM dendritic linker systems -: art. no. e10 [J].

Benters, R ;

Niemeyer, CM ;

Drutschmann, D ;

Blohm, D ;

Wöhrle, D .

NUCLEIC ACIDS RESEARCH, 2002, 30 (02) :10

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