Robotic System for MRI-Guided Focal Laser Ablation in the Prostate

被引:48
作者
Chen, Yue [1 ]
Squires, Alexander [1 ]
Seifabadi, Reza [2 ]
Xu, Sheng [2 ]
Agarwal, Harsh Kumar [3 ,4 ]
Bernardo, Marcelino [2 ]
Pinto, Peter A. [2 ]
Choyke, Peter [2 ,5 ]
Wood, Bradford [2 ]
Tse, Zion Tsz Ho [1 ]
机构
[1] Univ Georgia, Coll Engn, Athens, GA 30605 USA
[2] NIH, Dept Radiol & Imaging Sci, Ctr Intervent Oncol, Bldg 10, Bethesda, MD 20892 USA
[3] Philips Res North Amer, Briarcliff Manor, NY 10510 USA
[4] Samsung Res & Dev Inst, Bangalore 560037, Karnataka, India
[5] NCI, Ctr Canc Res, Bethesda, MD 20892 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
Focal laser ablation (FLA); image guided therapy; MRI; prostate cancer; robot; CANCER; THERAPY; MOTOR;
D O I
10.1109/TMECH.2016.2611570
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
MRI-conditional robotic platforms have proved to be an effective approach for image-guided interventions. In this study, a computer-assisted, pneumatically actuated robot is designed, built, and tested for MRI-guided prostate cancer focal laser ablation (FLA). The robotic manipulator provides two active planar degrees of freedom (DoFs) by using a customized CoreXY frame and one passive rotational DoF. A remote insertion mechanism improves the surgical workflow by keeping the patients inside the scanner during needle insertion. The robotic manipulator is tested in a 3T MR scanner to evaluate its MR compliance, and the results demonstrated that the signal-to-noise ratio (SNR) variation is less than 8%. The in-scanner template positioning accuracy test demonstrates that the manipulator achieves high targeting accuracy with a mean error of 0.46 mm and a standard deviation of 0.25 mm. Phantom studies have shown that the needle insertion accuracy of the manipulator is within 2 mm (mean = 1.7 mm, standard deviation = 0.2 mm).
引用
收藏
页码:107 / 114
页数:8
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