DNAzyme catalytic beacon sensors that resist temperature-dependent variations

被引：47
作者：
Nagraj, Nandini [1 ]
Liu, Juewen [1 ]
Sterling, Stephanie [1 ]
Wu, Jenny [1 ]
Lu, Yi [1 ]
机构：
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
来源：
CHEMICAL COMMUNICATIONS | 2009年 / 27期
基金：
美国国家科学基金会;
关键词：
FLUORESCENT SENSORS; MOLECULAR BEACONS; METAL-IONS; DNA; MISMATCHES; DESIGN; LEAD; THERMODYNAMICS; SENSITIVITY; BIOSENSORS;
D O I：
10.1039/b903059j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The temperature-dependent variability of a Pb2+-specific 8-17E DNAzyme catalytic beacon sensor has been addressed through the introduction of mismatches in the DNAzyme, and the resulting sensors resist temperature-dependent variations from 4 to 30 degrees C.
引用
收藏
页码：4103 / 4105
页数：3
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