Mitochondrial control of apoptosis

被引：1386
作者：
Kroemer, G
Zamzami, N
Susin, SA
机构：
[1] CNRS UPR 420, F-94801 Villejuif, 19 rue Guy Moquet
来源：
IMMUNOLOGY TODAY | 1997年 / 18卷 / 01期
关键词：
D O I：
10.1016/S0167-5699(97)80014-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The apoptotic process can be subdivided into three phases: a death-stimulus-dependent, heterogeneous induction phase, a common effector phase during which the 'decision to die' is taken, and a common degradation phase during which cells acquire the biochemical and morphological features of end-stage apoptosis. Here, Guido Kroemer, Naoufal Zamzami and Santos Susin discuss the implication of mitochondrial events in the apoptotic effector phase.
引用
收藏
页码：44 / 51
页数：8
相关论文
共 71 条
[1]   OVEREXPRESSED FULL-LENGTH HUMAN BCL2 EXTENDS THE SURVIVAL OF BACULOVIRUS-INFECTED SF9 INSECT CELLS [J].
ALNEMRI, ES ;
ROBERTSON, NM ;
FERNANDES, TF ;
CROCE, CM ;
LITWACK, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (16) :7295-7299
[2]  
AMEISEN JC, 1995, CELL DEATH DIFFER, V2, P285
[3]   GLUTAMATE-INDUCED NEURONAL DEATH - A SUCCESSION OF NECROSIS OR APOPTOSIS DEPENDING ON MITOCHONDRIAL-FUNCTION [J].
ANKARCRONA, M ;
DYPBUKT, JM ;
BONFOCO, E ;
ZHIVOTOVSKY, B ;
ORRENIUS, S ;
LIPTON, SA ;
NICOTERA, P .
NEURON, 1995, 15 (04) :961-973
[4]   BIOGENESIS OF MITOCHONDRIA [J].
ATTARDI, G ;
SCHATZ, G .
ANNUAL REVIEW OF CELL BIOLOGY, 1988, 4 :289-333
[5]  
BAFFY G, 1993, J BIOL CHEM, V268, P6511
[6]  
BERNARDI P, 1996, J BIOENERG BIOMEMBR, V28, P129
[7]   Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage [J].
Carayon, P ;
Portier, M ;
Dussossoy, D ;
Bord, A ;
Petitpretre, G ;
Canat, X ;
LeFur, G ;
Casellas, P .
BLOOD, 1996, 87 (08) :3170-3178
[8]  
Castedo M, 1996, J IMMUNOL, V157, P512
[9]  
Chinnaiyan AM, 1996, J BIOL CHEM, V271, P4573
[10]  
COHEN JJ, 1993, IMMUNOL TODAY, V14, P126, DOI 10.1016/0167-5699(93)90214-6
12345678