Thrombotic complications of COVID-19

被引:99
作者
Avila, Jacob [1 ]
Long, Brit [2 ]
Holladay, Dallas [3 ]
Gottlieb, Michael [3 ]
机构
[1] Univ Kentucky, Dept Emergency Med, Lexington, KY 40506 USA
[2] Brooke Army Med Ctr, Dept Emergency Med, Ft Sam Houston, TX 78234 USA
[3] Rush Univ, Dept Emergency Med, Med Ctr, Chicago, IL 60612 USA
关键词
COVID-19; SARS-CoV-2; Coronavirus; Thrombotic; Thrombosis; Emergency medicine; DISSEMINATED INTRAVASCULAR COAGULATION; ACUTE MYOCARDIAL-INFARCTION; CORONAVIRUS DISEASE 2019; FUNCTIONAL RECEPTOR; SARS CORONAVIRUS; ACE2; ANTICOAGULANT; SOCIETY; RISK;
D O I
10.1016/j.ajem.2020.09.065
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: The novel coronavirus disease of 2019 (COVID-19) is associated with significant morbidity and mortality. The impact of thrombotic complications has been increasingly recognized as an important component of this disease. Objective: This narrative review summarizes the thrombotic complications associated with COVID-19 with an emphasis on information for Emergency Medicine clinicians. Discussion: Thrombotic complications from COVID-19 are believed to be due to a hyperinflammatory response caused by the virus. Several complications have been described in the literature. These include acute limb ischemia, abdominal and thoracic aortic thrombosis, mesenteric ischemia, myocardial infarction, venous thromboembolism, acute cerebrovascular accident, and disseminated intravascular coagulation. Conclusion: It is important for Emergency Medicine clinicians to be aware of the thrombotic complications of COVID-19. Knowledge of these components are essential to rapidly recognize and treat to reduce morbidity and mortality in these patients. (C) 2020 Elsevier Inc. All rights reserved.
引用
收藏
页码:213 / 218
页数:6
相关论文
共 94 条
[1]  
A Beccara Lia, 2020, Eur J Case Rep Intern Med, V7, P001690, DOI 10.12890/2020_001690
[2]  
American Society ofHematology, OpenAI embeddings: Frequently asked questions
[3]  
Andrea V, 2020, INT J INFECT DIS, pS1201, DOI [10.1016/j.ijid.2020.05.0607, DOI 10.1016/J.IJID.2020.05.0607]
[4]  
[Anonymous], 2018, Front Pediatr, DOI [DOI 10.3389/FPED.2018.00142, 10.3389/fped.2018.00142]
[5]  
[Anonymous], 2020, THROMB RES
[6]  
[Anonymous], J THROMB HAEMOST, DOI DOI 10.1001/JAMA
[7]  
[Anonymous], 2020, JAMA NEUROL, DOI DOI 10.1001/JAMANEUROL.2020.0387
[8]  
[Anonymous], 2020, STROKE, DOI DOI 10.1161/STROKEAHA.120.029838
[9]   Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors [J].
Artifoni, Mathieu ;
Danic, Gwenvael ;
Gautier, Giovanni ;
Gicquel, Pascal ;
Boutoille, David ;
Raffi, Francois ;
Neel, Antoine ;
Lecomte, Raphael .
JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2020, 50 (01) :211-216
[10]   ST-Segment Elevation in Patients with Covid-19-A Case Series [J].
Bangalore, Sripal ;
Sharma, Atul ;
Slotwiner, Alexander .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (25) :2478-2480