Long-Term Follow-Up of Children, Adolescents, and Young Adult Cancer Survivors

被引：18

作者：

Hilgendorf, Inken ^{[1
]}

Bergelt, Corinna ^{[2
]}

Bokemeyer, Carsten ^{[3
]}

Kaatsch, Peter ^{[4
]}

Seifart, Ulf ^{[5
]}

Stein, Alexander ^{[6
]}

Langer, Thorsten ^{[7
]}

机构：

[1] Univ Klinikum Jena, Abt Hamatol & Onkol, Klin Innere Med 2, Jena, Germany

[2] Univ Klinikum Hamburg Eppendorf, Inst & Poliklin Med Psychol, Zentrum Psychosoziale Med, Hamburg, Germany

[3] Univ Klinikum Hamburg Eppendorf, Med Klin & Poliklin, Hubertus Wald Tumor Zentrum 2, Hamburg, Germany

[4] Johannes Gutenberg Univ Mainz, Deutsch Kinderkrebsregister, Univ Med, Inst Med Biometrie Epidemiol & Informat, Mainz, Germany

[5] Klin Sonnenblick Deutsch Rentenversicherung Hesse, Klin Hamatol & Onkol, Marburg, Germany

[6] Hamatol Onkol Praxis Hamburg Eppendorf, Hamburg, Germany

[7] Univ Klinikum Schleswig Holstein, Klin Kinder & Jugendmed, Campus Lubeck, Lubeck, Germany

来源：

ONCOLOGY RESEARCH AND TREATMENT | 2021年 / 44卷 / 04期

关键词：

AYA cancer survivor; Childhood cancer survivor; Late effects; Long-term follow-up;

D O I：

10.1159/000514381

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background and Summary: Thanks to increasing cure rates to currently >80%, children, adolescents, and young adults (CAYA) survive their cancer much more frequently today than decades ago. Due to their long life expectancy, CAYA cancer survivors are at a particular risk of long-term sequelae from the cancer itself or the therapy applied; this requires specific follow-up, and preventative or even therapeutic interventions. Thus, compared to the normal population, morbidity and mortality may be significantly increased. In 2 of 3 survivors, the cancer and the respective treatment can lead to late effects, even after 30 years, which require specific therapy; in about one-third of these cases, these effects are classed as severe. Applying structured follow-up could identify these late effects at an early stage and initiate immediate treatment. In 2018, a working group dealing with long-term survival after cancer detected <40 years of age was founded within the framework of the National Cancer Plan of the German Federal Ministry of Health.

引用

页码：184 / 189

页数：6

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